Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
about
Antagonistic Effect of a Salivary Proline-Rich Peptide on the Cytosolic Ca2+ Mobilization Induced by Progesterone in Oral Squamous Cancer Cells4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studiesIdentification of the gene that codes for the σ2 receptor.Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversificationNorbenzomorphan Scaffold: Chemical Tool for Modulating Sigma Receptor-Subtype Selectivity.Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment.Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype-Selective LigandsProgesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine RetinaSW43-DOX ± loading onto drug-eluting bead, a potential new targeted drug delivery platform for systemic and locoregional cancer treatment - An in vitro evaluationConjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic.Synthesis and biological characterisation of 18F-SIG343 and 18F-SIG353, novel and high selectivity σ2 radiotracers, for tumour imaging properties.Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer's disease.Capillary zone electrophoresis on-line coupled to mass spectrometry: A perspective application for clinical proteomics.Natural Products and Their Mimics as Targets of Opportunity for Discovery.Small Molecules for Active Targeting in Cancer.Targeting Nanocarriers with Anisamide: Fact or Artifact?Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016).Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma.Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging.High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model.Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle.A systematic exploration of the effects of flexibility and basicity on sigma (σ) receptor binding in a series of substituted diamines.Sigma Receptor (σR) Ligands with Antiproliferative and Anticancer Activity.Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma.
P2860
Q28552921-855A6340-2C3D-48D4-A453-F320CBD6F33FQ28829344-4F97B7E1-C0E0-4209-8040-4217E1575CA2Q33887088-ECEDEA56-4F9A-4078-A158-F8C0820BEF18Q34207033-12838B43-4A7A-4F04-BA3B-0FDA1843166AQ34555731-B6BBF2B4-9ABF-4D70-8B44-911555FF0E9BQ36132213-A9D61996-85C6-4D49-8144-2D84906B2FE8Q36249357-87F60767-6370-4783-8236-C62310FC77F8Q36738536-F9C9A362-8D5D-4F4B-B734-11CA06616FDAQ36978618-6C64BDCF-20A0-48DC-905B-CA568A2C6053Q37150075-F47618CD-BFF6-4A1C-8F0A-96B4DA9CC2E9Q37376094-F2317EB6-B8FD-414D-9B3D-4D1E41AF3600Q37427252-5BCEFD02-481E-4A7A-9336-570C6765D8CBQ37645771-1700FB3D-2D4B-482E-A999-933FCB291A86Q38340351-7EC202D5-C312-4531-B3D8-119F8EF0F7B7Q38557129-B29D2B94-C32B-47F6-90EB-50814C0620E1Q38780383-480F8DD5-70C3-46A0-B2A4-D7B7F9695483Q39019352-033B3B15-C2BD-4512-9A55-FE4EFCAA8D80Q39067013-A4CA86A2-EDCB-40A3-9795-9FD056E597FBQ47130202-65F52775-3A25-4380-ABD1-83BDECFC3E94Q48298113-E77D634A-B703-44F1-89D0-555B5C21A536Q50094597-EE33DEE2-70A4-4C21-B13E-622CC1CC8D10Q50933679-244DB109-EBF7-4BED-8892-08CD27554037Q51420967-70EE63E5-EAB4-4AE8-A25E-09B4CEE3A473Q52757903-540D91F1-C8E2-4F1A-A461-E219810F7AEEQ54251377-3A566F32-8646-4A73-8C09-AFC8002B5701
P2860
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@ast
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@en
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@nl
type
label
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@ast
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@en
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@nl
prefLabel
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@ast
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@en
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
@nl
P2093
P2860
P356
P1476
Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy
@en
P2093
Lang-Jun Zhang
Zongwen Wu
P2860
P304
P356
10.1002/MED.21297
P577
2013-08-06T00:00:00Z