Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
about
The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasomeControl of NOD2 and Rip2-dependent innate immune activation by GEF-H1A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responsesNOD-Like Receptors: Master Regulators of Inflammation and CancerRIP2 activity in inflammatory disease and implications for novel therapeuticsInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseDual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear CellsEngagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transductionThe c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization processA LysM and SH3-domain containing region of the Listeria monocytogenes p60 protein stimulates accessory cells to promote activation of host NK cells.NOD2-mediated suppression of CD55 on neutrophils enhances C5a generation during polymicrobial sepsis.Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways.E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.NOD-like receptors in intestinal homeostasis and epithelial tissue repair.NOD1 and NOD2: signaling, host defense, and inflammatory disease.Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains.Receptor interacting protein-2 plays a critical role in human lung epithelial cells survival in response to Fas-induced cell-death.Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis.NF-κB in immunobiology.Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma.Receptor-interacting protein 2 controls pulmonary host defense to Escherichia coli infection via the regulation of interleukin-17A.A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.Determining in vivo phosphorylation sites using mass spectrometry.Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagyStructures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease.Combined stimulation of Toll-like receptor 5 and NOD1 strongly potentiates activity of NF-κB, resulting in enhanced innate immune reactions and resistance to Salmonella enterica serovar Typhimurium infection.Ouabain-induced apoptosis in cochlear hair cells and spiral ganglion neurons in vitro.Innate immune-directed NF-κB signaling requires site-specific NEMO ubiquitination.Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release.Intracellular sensors of extracellular bacteria.Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis.Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated diseaseNOD proteins: regulators of inflammation in health and disease.The dual role of nod-like receptors in mucosal innate immunity and chronic intestinal inflammation.The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling.Insights into the molecular basis of the NOD2 signalling pathway.The E3 ligase Itch in immune regulation and beyond.
P2860
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P2860
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@ast
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@en
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@nl
type
label
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@ast
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@en
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@nl
prefLabel
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@ast
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@en
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@nl
P2860
P356
P1433
P1476
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.
@en
P2093
John M Asara
P2860
P304
P356
10.1101/GAD.1964410
P577
2010-12-01T00:00:00Z