Genome-wide mutational signatures of aristolochic acid and its application as a screening tool. - Wikidata - wikimedia - TriplyDB

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.

http://www.wikidata.org/entity/Q34362611

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Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances The Potential Power of Bar-HRM Technology in Herbal Medicine Identification Genomics of Cancer and a New Era for Cancer Prevention Chinese herbs containing aristolochic acid associated with renal failure and urothelial carcinoma: a review from epidemiologic observations to causal inference Balkan endemic nephropathy: an update on its aetiology Hypermutation in human cancer genomes: footprints and mechanisms Mutational signatures of ionizing radiation in second malignancies Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approaches Aristolochic acid exposure in Romania and implications for renal cell carcinoma Comparison of hepatocellular carcinoma in Eastern versus Western populations.Base changes in tumour DNA have the power to reveal the causes and evolution of cancer.Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.Modelling mutational landscapes of human cancers in vitro.NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention.Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.Developing traditional chinese medicine in the era of evidence-based medicine: current evidences and challenges.Mutation signatures implicate aristolochic acid in bladder cancer development APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.An integrated system for identifying the hidden assassins in traditional medicines containing aristolochic acids.MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes.Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.New Approaches for Biomonitoring Exposure to the Human Carcinogen Aristolochic Acid.The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.Genomic approaches to DNA repair and mutagenesis.Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid.Activity of Aristolochia bracteolata against Moraxella catarrhalis Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels.A comprehensive survey of the mutagenic impact of common cancer cytotoxics Rapid Identification of Officinal Akebiae Caulis and Its Toxic Adulterant Aristolochiae Manshuriensis Caulis (Aristolochia manshuriensis) by Loop-Mediated Isothermal Amplification.5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma.Mechanisms of base substitution mutagenesis in cancer genomes.

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Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.

http://www.wikidata.org/entity/Q34362611

description

2013 nî lūn-bûn

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2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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Genome-wide mutational signatu ...... plication as a screening tool.

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Ching-Fang Wu

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Ee Yan Siew

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Hong Lee Heng

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P2860

Cancer genome landscapes

A small-cell lung cancer genome with complex signatures of tobacco exposure

Aristolochic acid-associated urothelial cancer in Taiwan

Aristolochic acid and the etiology of endemic (Balkan) nephropathy

Structure and stability of DNA containing an aristolactam II-dA lesion: implications for the NER recognition of bulky adducts

Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

Frequent pathway mutations of splicing machinery in myelodysplasia

Aristolochia manshuriensis Kom inhibits adipocyte differentiation by regulation of ERK1/2 and Akt pathway.

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