TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation
about
Androgen receptor and prostate cancer stem cells: biological mechanisms and clinical implicationsGenetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse modelsMolecular pathways: targeting ETS gene fusions in cancer.Molecular pathways and targets in prostate cancerThe ETS family of oncogenic transcription factors in solid tumours.A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites.Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells.The genomic landscape of prostate cancerMechanisms of oncogenic chromosomal translocations.Wnt signaling in castration-resistant prostate cancer: implications for therapy.The oncogene ERG: a key factor in prostate cancer.The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.microRNA 338-3p exhibits tumor suppressor role and its down-regulation is associated with adverse clinical outcome in prostate cancer patients.TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation.ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss.ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.miRNAs as drivers of TMPRSS2-ERG negative prostate tumors in African American men.PREVENTING THE CHROMOSOMAL TRANSLOCATIONS THAT CAUSE CANCERERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN.Sphere-Formation Assay: Three-Dimensional Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells
P2860
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P2860
TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@ast
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@en
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@nl
type
label
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@ast
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@en
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@nl
prefLabel
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@ast
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@en
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@nl
P2093
P2860
P1433
P1476
TMPRSS2- driven ERG expression ...... ration resistant subpopulation
@en
P2093
Heather S Tillman
Hibah O Awwad
Kathleen Kelly
Luhua Zhang
Orla M Casey
Paul G Hynes
Philip L Martin
Wassim G Abou-Kheir
P2860
P304
P356
10.1371/JOURNAL.PONE.0041668
P407
P577
2012-07-30T00:00:00Z