TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation - Wikidata - wikimedia - TriplyDB

TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation

TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation

http://www.wikidata.org/entity/Q34364174

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Androgen receptor and prostate cancer stem cells: biological mechanisms and clinical implications Genetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse models Molecular pathways: targeting ETS gene fusions in cancer.Molecular pathways and targets in prostate cancer The ETS family of oncogenic transcription factors in solid tumours.A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites.Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells.The genomic landscape of prostate cancer Mechanisms of oncogenic chromosomal translocations.Wnt signaling in castration-resistant prostate cancer: implications for therapy.The oncogene ERG: a key factor in prostate cancer.The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.microRNA 338-3p exhibits tumor suppressor role and its down-regulation is associated with adverse clinical outcome in prostate cancer patients.TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation.ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss.ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.miRNAs as drivers of TMPRSS2-ERG negative prostate tumors in African American men.PREVENTING THE CHROMOSOMAL TRANSLOCATIONS THAT CAUSE CANCER ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN.Sphere-Formation Assay: Three-Dimensional Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells

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TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation

http://www.wikidata.org/entity/Q34364174

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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type

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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JOURNAL.PONE.0041668

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TMPRSS2- driven ERG expression ...... ration resistant subpopulation

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Heather S Tillman

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Hibah O Awwad

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Kathleen Kelly

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Lei Fang

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Luhua Zhang

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Orla M Casey

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Paul G Hynes

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Philip L Martin

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Ross Lake

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Wassim G Abou-Kheir

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P2860

Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

A census of human cancer genes

Role of the TMPRSS2-ERG gene fusion in prostate cancer

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells

Integrative genomic profiling of human prostate cancer

Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues.

Delineation of TMPRSS2-ERG splice variants in prostate cancer.

The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis

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e41668

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scholarly article

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10.1371/JOURNAL.PONE.0041668

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7

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7

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Gyorgy Petrovics

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2012-07-30T00:00:00Z

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230616883

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22860005

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3408501

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