B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers. - Wikidata - wikimedia - TriplyDB

B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.

B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.

http://www.wikidata.org/entity/Q34364711

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Follicular Helper T (Tfh) Cells in Autoimmune Diseases and Allograft Rejection Predominant Role of Plasmacytoid Dendritic Cells in Stimulating Systemic Autoimmunity B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production Pathways leading to an immunological disease: systemic lupus erythematosus.Altered B cell signalling in autoimmunity.TLR7 influences germinal center selection in murine SLE.Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Reversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes.New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome Female Bias in Systemic Lupus Erythematosus is Associated with the Differential Expression of X-Linked Toll-Like Receptor 8 Polymorphisms in Toll-like receptor genes are associated with vitiligo Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity.RNA sensing by conventional dendritic cells is central to the development of lupus nephritis Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice.IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity.The effect of BAFF inhibition on autoreactive B cell selection in murine SLE.Activation of TLR7 increases CCND3 expression via the downregulation of miR-15b in B cells of systemic lupus erythematosus.Developing connections amongst B lymphocytes and deregulated pathways in autoimmunity.B cells expressing the transcription factor T-bet drive lupus-like autoimmunity.B cells biology in systemic lupus erythematosus-from bench to bedside.The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling.Self-reactive VH4-34-expressing IgG B cells recognize commensal bacteria.Deficiency in IRAK4 activity attenuates manifestations of murine Lupus.Spontaneous germinal centers and autoimmunity.Kidney Expression of Toll Like Receptors in Lupus Nephritis: Quantification and Clinicopathological Correlations.Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models.Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation.Autoimmunity in 2014.Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex-biased autoimmunity.Co-Stimulation of BCR and Toll-Like Receptor 7 Increases Somatic Hypermutation, Memory B Cell Formation, and Secondary Antibody Response to Protein Antigen.Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers.Cutting Edge: Endogenous IFN-β Regulates Survival and Development of Transitional B Cells.Glucocorticoid-induced leucine zipper (GILZ) inhibits B cell activation in systemic lupus erythematosus.Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice.TLR7, a third signal for the robust generation of spontaneous germinal center B cells in systemic lupus erythematosus.Negative regulation of B cell responses and self-tolerance to RNA-related lupus self-antigen.Toll-like receptors in lupus nephritis.Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ.

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B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.

http://www.wikidata.org/entity/Q34364711

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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type

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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B cell-intrinsic TLR7 signalin ...... spontaneous germinal centers.

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JIMMUNOL.1401720

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Journal of Immunology

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B cell-intrinsic TLR7 signalin ...... f spontaneous germinal centers

@en

P2093

Chetna Soni

http://www.w3.org/2001/XMLSchema#string

Eric B Wong

http://www.w3.org/2001/XMLSchema#string

Shizuo Akira

http://www.w3.org/2001/XMLSchema#string

Tahsin N Khan

http://www.w3.org/2001/XMLSchema#string

Takashi Satoh

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Ziaur S M Rahman

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P2860

A Toll-like receptor recognizes bacterial DNA

BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

Toll-like receptor downstream signaling.

Contribution of Toll-like receptor signaling to germinal center antibody responses

The danger model: a renewed sense of self

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

B-cell tolerance checkpoints in health and autoimmunity

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

Germinal centers

The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.

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4400-4414

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10.4049/JIMMUNOL.1401720

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9

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193

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Phillip P. Domeier

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266123987

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25252960

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Toll-like receptor

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4201954

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