Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). - Wikidata - wikimedia - TriplyDB

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

http://www.wikidata.org/entity/Q34365459

about

Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells Thyroid transcription factor in differentiating type II cells: regulation, isoforms, and target genes Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiation Sequence-specific inhibition of small RNA function A rapid and sensitive assay for quantification of siRNA efficiency and specificity Decoding the riddle: the dawn of RNAi for the study of gene-gene and gene-environment interactions Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis siRNA-mediated off-target gene silencing triggered by a 7 nt complementation Tolerated wobble mutations in siRNAs decrease specificity, but can enhance activity in vivo.Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals.Co-expression of anti-NFkappaB RNA aptamers and siRNAs leads to maximal suppression of NFkappaB activity in mammalian cells.Specific in vivo knockdown of protein function by intrabodies Nucleic acid targeting: towards personalized therapy for head and neck cancer.Targeting cancer gene therapy with magnetic nanoparticles RNA mediated Toll-like receptor stimulation in health and disease Abasic pivot substitution harnesses target specificity of RNA interference Human RGM249-derived small RNAs potentially regulate tumor malignancy siRNA off-target effects can be reduced at concentrations that match their individual potency RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells Predicting oligonucleotide-directed mutagenesis failures in protein engineering.Specific and nontoxic silencing in mammalian cells with expressed long dsRNAs.SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.Analysis of siRNA specificity on targets with double-nucleotide mismatches Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis.Off-target effects of siRNA specific for GFP Designer siRNAs to overcome the challenges from the RNAi pathway.Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading.Sequence-non-specific effects of RNA interference triggers and microRNA regulators.A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.Asymmetric shorter-duplex siRNA structures trigger efficient gene silencing with reduced nonspecific effects.G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway.Puromycin-resistant lentiviral control shRNA vector, pLKO.1 induces unexpected cellular differentiation of P19 embryonic stem cells.Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology.Accelerating cancer modeling with RNAi and nongermline genetically engineered mouse models.High-dose siRNAs upregulate mouse Eri-1 at both transcription and posttranscription levels Genomic analysis of anti-hepatitis B virus (HBV) activity by small interfering RNA and lamivudine in stable HBV-producing cells.Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development Knockdown of caveolin-1 by siRNA inhibits the transformation of mouse hepatoma H22 cells in vitro and in vivo

P2860

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P2860

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

http://www.wikidata.org/entity/Q34365459

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

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Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

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Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

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type

label

Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

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Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

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Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

@nl

prefLabel

Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

@ast

Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

@en

Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

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P2860

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Nonspecific, concentration-dep ...... all interfering RNAs (siRNAs).

@en

P2093

Michael R Green

http://www.w3.org/2001/XMLSchema#string

Stephan P Persengiev

http://www.w3.org/2001/XMLSchema#string

Xiaochun Zhu

http://www.w3.org/2001/XMLSchema#string

P2860

Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

RNA interference

PKR; a sentinel kinase for cellular stress

RNA silencing: the genome's immune system

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

Expression profiling reveals off-target gene regulation by RNAi

DNA arrays for analysis of gene expression

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

A unique ISRE, in the TATA-less human Isg20 promoter, confers IRF-1-mediated responsiveness to both interferon type I and type II.

P304

12-18

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scholarly article

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10.1261/RNA5160904

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P433

1

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10

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277449920

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14681580

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1370513

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