Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability - Wikidata - wikimedia - TriplyDB

Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability

Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability

http://www.wikidata.org/entity/Q34366187

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Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions Simulating structural and thermodynamic properties of carcinogen-damaged DNA.Intercalative conformations of the 14R (+)- and 14S (-)-trans-anti-DB[a,l]P-N⁶-dA adducts: molecular modeling and MD simulations.Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery.Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline.Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells.Dynamic conformational heterogeneities of carcinogen-DNA adducts and their mutagenic relevance.Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene.Regulation and disregulation of mammalian nucleotide excision repair: a pathway to nongermline breast carcinogenesis.Influence of structural and functional modifications of selected genotoxic carcinogens on metabolism and mutagenicity - a review.DNA adduct structure-function relationships: comparing solution with polymerase structures.Effects of benzo(e)pyrene on the retinal neurosensory cells and human microvascular endothelial cells in vitro.Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences.Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability Generation, repair and replication of guanine oxidation products.Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations.Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair.

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Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability

http://www.wikidata.org/entity/Q34366187

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2002 nî lūn-bûn

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2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2002 թվականի օգոստոսին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Relating repair susceptibility ...... on and thermodynamic stability

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Nucleic Acids Research

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Relating repair susceptibility ...... on and thermodynamic stability

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Dinshaw J Patel

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Min Wu

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Nicholas E Geacintov

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Suse Broyde

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P2860

A more unified picture for the thermodynamics of nucleic acid duplex melting: a characterization by calorimetric and volumetric techniques.

NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex

NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual s

Adduction of the human N-ras codon 61 sequence with (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a] pyrene: structural refinement of the intercalated SRSR(61,2) (-)-(7S,8R,9S,10R)-N6-[10-(7,8,9,10- tetrahydrobenzo[a]pyrenyl)]

Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine

A multistep damage recognition mechanism for global genomic nucleotide excision repair

Sequential assembly of the nucleotide excision repair factors in vivo

Classical electrostatics in biology and chemistry

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids

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10.1093/NAR/GKF427

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