Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias

Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias

Item
http://www.wikidata.org/entity/Q34374079
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemiaPhase I evaluation of STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in dogs with spontaneous cancerMultifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signalingRetargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor.Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene.WTAP is a novel oncogenic protein in acute myeloid leukemiaThe transcription factor Wilms tumor 1 confers resistance in myeloid leukemia cells against the proapoptotic therapeutic agent TRAIL (tumor necrosis factor α-related apoptosis-inducing ligand) by regulating the antiapoptotic protein Bcl-xLGanetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer.HSP-90 inhibitor ganetespib is synergistic with doxorubicin in small cell lung cancer.Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis.Efficacy of an HSP90 inhibitor, ganetespib, in preclinical thyroid cancer models.The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias.DNA and RNA binding by the Wilms' tumour gene 1 (WT1) protein +KTS and -KTS isoforms-From initial observations to recent global genomic analyses.The CUG-translated WT1, not AUG-WT1, is an oncogene.WT1 protein is cleaved by caspase-3 in apoptotic leukemic cells.Wilms' tumor 1 drives fibroproliferation and myofibroblast transformation in severe fibrotic lung disease
P2860

Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias

Item
http://www.wikidata.org/entity/Q34374079
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@ast
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@en
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@nl
type
label
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@ast
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@en
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@nl
prefLabel
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@ast
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@en
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Heat shock protein 90 regulate ...... 1 protein in myeloid leukemias
@en
P2093
P2860
P304
P31
P356
10.1182/BLOOD-2009-10-247239
P407
P433
P478
P577
P5875
P698
P921
P932