Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
about
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetamMonotherapy for partial epilepsy: focus on levetiracetamDiverse mechanisms of antiepileptic drugs in the development pipelineSynaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and BeyondAnti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A.Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture.Molecular targets versus models for new antiepileptic drug discoveryTreatment of Convulsive and Nonconvulsive Status Epilepticus.Neuroprotection by valproic Acid in mouse models of permanent and transient focal cerebral ischemia.Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs.The current state of treatment of status epilepticus.Levetiracetam: treatment in epilepsy.A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damageAge-dependent effects of topiramate on the acquisition and the retention of rapid kindling.The New Antiepileptic Drugs: Their Neuropharmacology and Clinical Indications.Levetiracetam in the treatment of childhood epilepsy.Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam.Levetiracetam results in increased and decreased alcohol drinking with different access procedures in C57BL/6J miceLevetiracetam for treatment of premenstrual dysphoric disorder: a pilot, open-label study.Modulation of action potential and calcium signaling by levetiracetam in rat sensory neurons.Levetiracetam for levodopa-induced dyskinesia in Parkinson's disease: a randomized, double-blind, placebo-controlled trial.Discovery of indolone acetamides as novel SV2A ligands with improved potency toward seizure suppression.Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy.Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus.Implications of antiinflammatory properties of the anticonvulsant drug levetiracetam in astrocytes.Exacerbations of seizures by levetiracetam.A companion to the preclinical common data elements for pharmacologic studies in animal models of seizures and epilepsy. A Report of the TASK3 Pharmacology Working Group of the ILAE/AES Joint Translational Task Force
P2860
Q24561949-7CA50B03-DAF6-4840-B2B7-D1BF918B7EA2Q24644605-42DA038E-2E5C-4354-AFC3-228E3537768CQ24675330-11E80640-5EA5-4134-BE10-91949BD7B416Q28068507-1A649D8F-C83E-4C27-B54D-89EC2EF83FB1Q28281249-24485BB9-C977-42A8-AFA9-01C1EFF75A9EQ33761706-9B1EE729-DC0D-428C-B735-F5FF1F43870FQ34375049-1D5F39C9-1F4D-46DD-82FA-438DF3C2C758Q34427751-558CDCCF-E649-45CE-9894-E84E8AFE0AE7Q34554054-AB87496E-1B40-4CA1-B35F-ADFBF42FBDF3Q34559190-AF245E82-2F0F-4B38-A538-40CFC365DFBCQ34666494-943C59ED-31EE-4DA8-958F-B2CDE91663AFQ35575012-AA10A7AC-4478-4137-82CA-43D62BFD8431Q35659046-CEC21B99-306F-4C25-92F5-FA3F943458ECQ36647742-FBD409AE-109F-4337-BF67-4572B8790E03Q36909520-C1A80CFC-70F4-4EDC-8409-B929B6AC5467Q37126800-19C71FD4-4043-4F6F-A715-C9DBA666504DQ37216736-71EB4467-85AB-4D08-B50F-106B3D7DB8B6Q37448220-4C4A3895-51ED-44E6-A3B2-7F01B0E40DADQ40089627-47B1E931-1DD7-4945-B6E7-725CEAEFF4ABQ42504486-FD45142B-3B8F-4490-8DE6-7BC3B2E0AD19Q42922693-0E49D269-0819-4B3F-92A1-E7496F04CFB6Q43205870-9E1AC561-D3A1-409D-8926-ED2CF86AFCECQ44416102-F5CF6CFD-BBB7-4AF1-B3F5-BE66F5AE8158Q46007508-11D484F9-E48B-4F41-A62A-328765431A33Q46706461-B95B9670-4F32-4D99-82FE-094C34E0C227Q46816187-D084E1E9-09CD-4F03-AD30-BA33A1A0ABECQ59137534-34119D7B-BD5D-4AF6-9B3C-10736B67DA47
P2860
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@ast
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@en
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@nl
type
label
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@ast
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@en
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@nl
prefLabel
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@ast
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@en
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@nl
P1433
P1476
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
@en
P2093
Klitgaard H
P356
10.1046/J.1528-1157.2001.00003.X
P478
42 Suppl 4
P577
2001-01-01T00:00:00Z