Physiological levels of ATP negatively regulate proteasome function. - Wikidata - wikimedia - TriplyDB

Physiological levels of ATP negatively regulate proteasome function.

Physiological levels of ATP negatively regulate proteasome function.

http://www.wikidata.org/entity/Q34376187

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Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?Regulation of the proteasome by ATP: implications for ischemic myocardial injury and donor heart preservation The ubiquitin-proteasome system and cardiovascular disease Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies The ubiquitin proteasome system and myocardial ischemia Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases.Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth Proteasome inhibition prolongs survival during lethal hemorrhagic shock in rats L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro.HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivo Enhancement of proteasome function by PA28α overexpression protects against oxidative stress.Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Intracellular ATP concentration contributes to the cytotoxic and cytoprotective effects of adenosine Proteasome functional insufficiency in cardiac pathogenesis.Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition MicroRNA-mRNA regulatory networking fine-tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities.A microRNA-mediated decrease in eukaryotic initiation factor 2α promotes cell survival during PS-341 treatment.Age influences inflammatory responses, hemodynamics, and cardiac proteasome activation during acute lung injury.Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.Gambogic acid enhances proteasome inhibitor-induced anticancer activity.Gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition Gambogic acid moderates cardiac responses to chronic hypoxia likely by acting on the proteasome and NF-κB pathway.Gambogic acid suppresses pressure overload cardiac hypertrophy in rats.The Danger Signal Extracellular ATP Is an Inducer of Fusobacterium nucleatum Biofilm Dispersal.Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation.Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy.Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases.Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor.The role of the proteasome in heart disease Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force.The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention.The anticancer effect of cytotoxin 1 from Naja atra Cantor venom is mediated by a lysosomal cell death pathway involving lysosomal membrane permeabilization and cathepsin B release.Controlling amphiphilic copolymer self-assembly morphologies based on macrocycle/anion recognition and nucleotide-induced payload release.Prolongation of myocardial viability by proteasome inhibition during hypothermic organ preservation.Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation.Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein.

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P2860

Physiological levels of ATP negatively regulate proteasome function.

http://www.wikidata.org/entity/Q34376187

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Physiological levels of ATP negatively regulate proteasome function.

@ast

Physiological levels of ATP negatively regulate proteasome function.

@en

Physiological levels of ATP negatively regulate proteasome function.

@nl

type

label

Physiological levels of ATP negatively regulate proteasome function.

@ast

Physiological levels of ATP negatively regulate proteasome function.

@en

Physiological levels of ATP negatively regulate proteasome function.

@nl

prefLabel

Physiological levels of ATP negatively regulate proteasome function.

@ast

Physiological levels of ATP negatively regulate proteasome function.

@en

Physiological levels of ATP negatively regulate proteasome function.

@nl

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Physiological levels of ATP negatively regulate proteasome function

@en

P2093

Canguo Zhao

http://www.w3.org/2001/XMLSchema#string

Change Zhang

http://www.w3.org/2001/XMLSchema#string

Changshan Yang

http://www.w3.org/2001/XMLSchema#string

Emily McDowell

http://www.w3.org/2001/XMLSchema#string

Guangmei Wen

http://www.w3.org/2001/XMLSchema#string

Haiping Guo

http://www.w3.org/2001/XMLSchema#string

Hongbiao Huang

http://www.w3.org/2001/XMLSchema#string

Jinbao Liu

http://www.w3.org/2001/XMLSchema#string

Li Lu

http://www.w3.org/2001/XMLSchema#string

Ningfang Ma

http://www.w3.org/2001/XMLSchema#string

P2860

Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6

Diversity of degradation signals in the ubiquitin-proteasome system

The ubiquitin system

Autophagy fights disease through cellular self-digestion

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1

Impairment of the ubiquitin-proteasome system by protein aggregation

In vivo pH and metabolite changes during a single contraction in rat uterine smooth muscle.

Degradation of oxidized proteins by the 20S proteasome.

ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.

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1372-1385

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scholarly article

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10.1038/CR.2010.123

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12

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20

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2010-08-31T00:00:00Z

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46095796

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20805844

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2996470

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