Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
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Human β-cell proliferation and intracellular signaling: part 3Recent developments in β-cell differentiation of pluripotent stem cells induced by small and large moleculesAdvances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.Generation of Functional Beta-Like Cells from Human Exocrine Pancreas.DNA methylation directs functional maturation of pancreatic β cells.The new biology of diabetes.Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.PNA lectin for purifying mouse acinar cells from the inflamed pancreas.ActivinB Is Induced in Insulinoma To Promote Tumor Plasticity through a β-Cell-Induced DedifferentiationTransient Suppression of TGFβ Receptor Signaling Facilitates Human Islet TransplantationInhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication.In Vitro Proliferation of Porcine Pancreatic Islet Cells for β-Cell Therapy Applications.MiRNAs in β-Cell Development, Identity, and Disease.Metabolic Stress and Compromised Identity of Pancreatic Beta Cells.Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation.Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas.Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters.Mechanisms of adult human β-cell in vitro dedifferentiation and redifferentiation.When β-cells fail: lessons from dedifferentiation.Generation of stem cell-derived β-cells from patients with type 1 diabetes.Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease.Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.β-Cell dedifferentiation, reduced duct cell plasticity, and impaired β-cell mass regeneration in middle-aged rats.Loss of end-differentiated β-cell phenotype following pancreatic islet transplantation.Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity.Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice.Type 2 diabetes mellitusCellular signaling pathways regulating β-cell proliferation as a promising therapeutic target in the treatment of diabetes
P2860
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P2860
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@ast
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@en
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@nl
type
label
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@ast
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@en
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@nl
prefLabel
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@ast
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@en
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
@nl
P2093
P2860
P356
P1433
P1476
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway
@en
P2093
Adam N Roose
Anthony C Arvanites
Barak Blum
Douglas A Melton
Jeffrey C Davis
Lance S Davidow
Ornella Barrandon
René Maehr
P2860
P304
P356
10.7554/ELIFE.02809
P407
P577
2014-09-16T00:00:00Z