Presynaptic alpha2delta-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions
about
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialHomeostatic plasticity at the Drosophila neuromuscular junctionPokes, sunburn, and hot sauce: Drosophila as an emerging model for the biology of nociceptionThe ß subunit of voltage-gated Ca2+ channelsEmerging evidence for specific neuronal functions of auxiliary calcium channel α₂δ subunits.The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for functionCalcium channel auxiliary α2δ and β subunits: trafficking and one step beyond.Synaptic organizing complexes.Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice.Characterization of Cav1.4 complexes (α11.4, β2, and α2δ4) in HEK293T cells and in the retinaA single-cross, RNA interference-based genetic tool for examining the long-term maintenance of homeostatic plasticityExpression and cellular localization of the voltage-gated calcium channel α2δ3 in the rodent retina.The effects of intrathecal and systemic gabapentin on spinal substance P release.The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection.Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture.Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.Expression of voltage-gated calcium channel α(2)δ(4) subunits in the mouse and rat retina.The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentialsAstrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model.Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacologyProteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.Molecular mechanism of active zone organization at vertebrate neuromuscular junctions.How voltage-gated calcium channels gate forms of homeostatic synaptic plasticitySynaptogenesis: new roles for an old player.Regulation of synaptic connectivity by gliaThe synaptic cytoskeleton in development and disease.Transsynaptic channelosomes: non-conducting roles of ion channels in synapse formationExtracellular matrix and its receptors in Drosophila neural developmentL-type CaV1.2 calcium channels: from in vitro findings to in vivo function.Thrombospondins and synaptogenesisThe Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.Neuroanatomy of pain-deficiency and cross-modal activation in calcium channel subunit (CACN) α2δ3 knockout mice.Surface dynamics of voltage-gated ion channelsThe role of laminins in the organization and function of neuromuscular junctions.Dynamic association of calcium channel subunits at the cellular membrane.Analysis of adhesion molecules and basement membrane contributions to synaptic adhesion at the Drosophila embryonic NMJ.Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology.α2δ-3 Is Required for Rapid Transsynaptic Homeostatic Signaling.
P2860
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P2860
Presynaptic alpha2delta-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@ast
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@en
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@nl
type
label
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@ast
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@en
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@nl
prefLabel
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@ast
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@en
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@nl
P2093
P2860
P356
P1433
P1476
Presynaptic alpha2delta-3 is r ...... of its Ca2+-channel functions
@en
P2093
Asli Oztan
Peri T Kurshan
Thomas L Schwarz
P2860
P2888
P304
P356
10.1038/NN.2417
P407
P577
2009-10-11T00:00:00Z