about
Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegansFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesGeroscience approaches to increase healthspan and slow agingUsing C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseasesProgramming and Reprogramming Cellular Age in the Era of Induced PluripotencySirtuins in epigenetic regulationC. elegans in high-throughput drug discoveryAngiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life SpanModulating Behavior in C. elegans Using Electroshock and Antiepileptic DrugsAllyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensorThe anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespanFDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicityDrug absorption efficiency in Caenorhbditis elegans delivered by different methodsUV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin SignalingAnti-epileptic drugs delay age-related loss of spiral ganglion neurons via T-type calcium channel.Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer's disease mouse model.Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expressionGenetic and pharmacological factors that influence reproductive aging in nematodesEvolutionary conservation of drug action on lipoprotein metabolism-related targets.Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster.Withania somnifera root extract extends lifespan of Caenorhabditis elegans.Dietary intake of resveratrol enhances the adaptive immunity of aged rats.Using Caenorhabditis elegans as a model for aging and age-related diseases.Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity.Beneficial effects of wheat gluten hydrolysate to extend lifespan and induce stress resistance in nematode Caenorhabditis elegans.A pharmacological network for lifespan extension in Caenorhabditis elegansIn vitro screening for drug repositioning.Association with pathogenic bacteria affects life-history traits and population growth in Caenorhabditis elegansComparative approaches to facilitate the discovery of prolongevity interventions: effects of tocopherols on lifespan of three invertebrate species.Pharmacological maintenance of protein homeostasis could postpone age-related diseaseAnti-aging effect of polysaccharide from Bletilla striata on nematode Caenorhabditis elegansA predictable worm: application of Caenorhabditis elegans for mechanistic investigation of movement disorders.Annual fishes of the genus Nothobranchius as a model system for aging research.Pharmacological intervention in invertebrate aging.Regulation of lifespan by chemosensory and thermosensory systems: findings in invertebrates and their implications in mammalian aging.Endocrine targets for pharmacological intervention in aging in Caenorhabditis elegans.Healthspan Pharmacology.Pharmacological lifespan extension of invertebratesCurcumin and neurodegenerative diseases.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Anticonvulsant medications extend worm life-span.
@ast
Anticonvulsant medications extend worm life-span.
@en
Anticonvulsant medications extend worm life-span.
@nl
type
label
Anticonvulsant medications extend worm life-span.
@ast
Anticonvulsant medications extend worm life-span.
@en
Anticonvulsant medications extend worm life-span.
@nl
prefLabel
Anticonvulsant medications extend worm life-span.
@ast
Anticonvulsant medications extend worm life-span.
@en
Anticonvulsant medications extend worm life-span.
@nl
P2093
P356
P1433
P1476
Anticonvulsant medications extend worm life-span.
@en
P2093
Cheng Huang
Douglas F Covey
Idella Yamben
Kerry Kornfeld
Kimberley Evason
P304
P356
10.1126/SCIENCE.1105299
P407
P577
2005-01-01T00:00:00Z