The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.
about
Molecular interactions of human Exo1 with DNACharacterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reactionCleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme AXeroderma pigmentosum group C protein interacts physically and functionally with thymine DNA glycosylaseREPAIRtoire--a database of DNA repair pathwaysLong patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complexHuman base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activityOxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2Inhibition of Ape1 nuclease activity by lead, iron, and cadmium.Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assaysHuman AP endonuclease 1: a potential marker for the prediction of environmental carcinogenesis riskDNA Damage and Pulmonary HypertensionOverview of base excision repair biochemistryLooking beneath the surface to determine what makes DNA damage deleteriousChallenges in DNA motion control and sequence readout using nanopore devicesInsight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleasesCharacterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function.Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediatesDNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extractsSingle nucleotide polymorphisms in DNA repair genes and prostate cancer riskRole of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesisA genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population.Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collectionA quantitative model of human DNA base excision repair. I. Mechanistic insights.Effects of mono- and divalent metal ions on DNA binding and catalysis of human apurinic/apyrimidinic endonuclease 1.Mutations in the alpha8 loop of human APE1 alter binding and cleavage of DNA containing an abasic site.Nitrosative cytosine deamination. An exploration of the chemistry emanating from deamination with pyrimidine ring-opening.Detection of labeled abasic sites in damaged DNA by capillary electrophoresis with laser-induced fluorescence.Requirement for abasic endonuclease gene homologues in Arabidopsis seed development.A specific DNA-nanoprobe for tracking the activities of human apurinic/apyrimidinic endonuclease 1 in living cells.Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?On the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic site with the opposing guanine residue of 5'-CAp sequences in duplex DNA.DNA polymerase β uses its lyase domain in a processive search for DNA damage.Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.Characterization of DNA damage induced by a natural product antitumor antibiotic leinamycin in human cancer cells.Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein bindingApurinic/apyrimidinic endonuclease/redox effector factor-1(APE/Ref-1): a unique target for the prevention and treatment of human melanoma.Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro.DNA repair deficiency in neurodegeneration.
P2860
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P2860
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@ast
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@en
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@nl
type
label
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@ast
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@en
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@nl
prefLabel
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@ast
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@en
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@nl
P1433
P1476
The major human abasic endonuc ...... pair of abasic lesions in DNA.
@en
P2093
Wilson DM 3rd
P304
P356
10.1016/S0921-8777(01)00063-5
P407
P577
2001-05-01T00:00:00Z