Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling.
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Taking the time to study competitive antagonismNMDA Receptor Function During Senescence: Implication on Cognitive PerformanceStructural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-D-Aspartate ReceptorsGlutamate receptor ion channels: structure, regulation, and functionPharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytesSusceptibility to Calcium Dysregulation during Brain Aging.Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists.The IGF-derived tripeptide Gly-Pro-Glu is a weak NMDA receptor agonistLong-Term Potentiation at CA3-CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress.Early Expression of Parkinson's Disease-Related Mitochondrial Abnormalities in PINK1 Knockout Rats.Characterization of the gating conformational changes in the felbamate binding site in NMDA channelsTCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive mannerGC-MS-Based Metabonomic Profiling Displayed Differing Effects of Borna Disease Virus Natural Strain Hu-H1 and Laboratory Strain V Infection in Rat Cortical NeuronsDirect pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonistInfluence of Volatile Anesthesia on the Release of Glutamate and other Amino Acids in the Nucleus Accumbens in a Rat Model of Alcohol Withdrawal: A Pilot Study.A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia.Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors.A family of photoswitchable NMDA receptors.Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds.Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.Unique Contributions of an Arginine Side Chain to Ligand Recognition in a Glutamate-gated Chloride Channel.The integrity of the glycine co-agonist binding site of N-methyl-D-aspartate receptors is a functional quality control checkpoint for cell surface delivery.Glutamate receptors at atomic resolution.Presynaptic N-Methyl-d-aspartate (NMDA) Receptor Activity Is Increased Through Protein Kinase C in Paclitaxel-induced Neuropathic PainComplexes of Cu(II) ions and noncovalent interactions in systems with L-aspartic acid and cytidine-5'-monophosphate.Age-related protective effect of deprenyl on changes in the levels of diagnostic marker enzymes and antioxidant defense enzymes activities in cerebellar tissue in Wistar rats.Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles.Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit.Biochemical Constituents and in Vitro Antioxidant and Anticholinesterase Potential of Seeds from Native Korean Persimmon Genotypes.Alterations in brain amino acid metabolism and inhibitory effects on PKC are possibly correlated with anticonvulsant effects of the isomeric mixture of α- and β-amyrin from Protium heptaphyllum.Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.Review: Amino acid concentration of high protein food products and an overview of the current methods used to determine protein quality.Effects of Bacterial Fermentation on the Biochemical Constituents and Antioxidant Potential of Fermented and Unfermented Soybeans Using Probiotic Bacillus subtilis (KCTC 13241).Aspartame and Soft Drink-Mediated Neurotoxicity in Rats: Implication of Oxidative Stress, Apoptotic Signaling Pathways, Electrolytes and Hormonal Levels.Central administration of L- and D-aspartate attenuates stress behaviors by social isolation and CRF in neonatal chicks.Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid.NMDA receptors mediate contractile responses in human airway smooth muscle cells.Tonically active NMDA receptors--a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum.
P2860
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P2860
Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structural features of the glu ...... enesis and molecular modeling.
@ast
Structural features of the glu ...... enesis and molecular modeling.
@en
Structural features of the glu ...... enesis and molecular modeling.
@nl
type
label
Structural features of the glu ...... enesis and molecular modeling.
@ast
Structural features of the glu ...... enesis and molecular modeling.
@en
Structural features of the glu ...... enesis and molecular modeling.
@nl
prefLabel
Structural features of the glu ...... enesis and molecular modeling.
@ast
Structural features of the glu ...... enesis and molecular modeling.
@en
Structural features of the glu ...... enesis and molecular modeling.
@nl
P2093
P356
P1476
Structural features of the glu ...... enesis and molecular modeling.
@en
P2093
Alexander R Johnston
Amanda L Jacob
Hongjie Yuan
James P Snyder
Matthew T Geballe
Philip E Chen
Phillip J Stansfeld
Stephen F Traynelis
P304
P356
10.1124/MOL.104.008185
P577
2005-02-09T00:00:00Z