Unwinding of synthetic replication and recombination substrates by Srs2.
about
Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loopsFunctional coupling of duplex translocation to DNA cleavage in a type I restriction enzymeLocal regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylationYeast mitochondrial HMG proteins: DNA-binding properties of the most evolutionarily divergent component of mitochondrial nucleoidsPro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.The helical domain of the EcoR124I motor subunit participates in ATPase activity and dsDNA translocation.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.Role of PCNA and RFC in promoting Mus81-complex activity.Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation.Hyperactive Cdc2 kinase interferes with the response to broken replication forks by trapping S.pombe Crb2 in its mitotic T215 phosphorylated state.Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2.Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms.The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51
P2860
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P2860
Unwinding of synthetic replication and recombination substrates by Srs2.
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Unwinding of synthetic replication and recombination substrates by Srs2.
@ast
Unwinding of synthetic replication and recombination substrates by Srs2.
@en
Unwinding of synthetic replication and recombination substrates by Srs2.
@nl
type
label
Unwinding of synthetic replication and recombination substrates by Srs2.
@ast
Unwinding of synthetic replication and recombination substrates by Srs2.
@en
Unwinding of synthetic replication and recombination substrates by Srs2.
@nl
prefLabel
Unwinding of synthetic replication and recombination substrates by Srs2.
@ast
Unwinding of synthetic replication and recombination substrates by Srs2.
@en
Unwinding of synthetic replication and recombination substrates by Srs2.
@nl
P2860
P1433
P1476
Unwinding of synthetic replication and recombination substrates by Srs2.
@en
P2093
Lumir Krejci
Victoria Marini
P2860
P304
P356
10.1016/J.DNAREP.2012.05.007
P577
2012-08-24T00:00:00Z