Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F.
about
Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motifThe TP53INP2 protein is required for autophagy in mammalian cellsTumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor developmentThe Emerging Role of miRNAs in HTLV-1 Infection and ATLL PathogenesisTranscriptional control of stem cell fate by E2Fs and pocket proteinsTP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expressionASPP: a new family of oncogenes and tumour suppressor genes.Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cellsLoss of robustness and addiction to IGF1 during early keratinocyte transformation by human Papilloma virus 16Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals.The novel tryptamine derivative JNJ-26854165 induces wild-type p53- and E2F1-mediated apoptosis in acute myeloid and lymphoid leukemias.Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in response to DNA damage.Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2.Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseasesPlacental gene expression responses to maternal protein restriction in the mouse.Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.Life and death decisions by the E2F transcription factors.E2F1 death pathways as targets for cancer therapyTumor Protein 53-Induced Nuclear Protein 1 Enhances p53 Function and Represses Tumorigenesis.Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomasChemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and APCmin/+ mouse intestinal tumorigenesis.The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis.Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts.Caffeic acid phenethyl ester induces E2F-1-mediated growth inhibition and cell-cycle arrest in human cervical cancer cells.An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.Differential effects of c-Ras upon transformation, adipocytic differentiation, and apoptosis mediated by the simian virus 40 large tumor antigen.E2F1 modulates p38 MAPK phosphorylation via transcriptional regulation of ASK1 and Wip1.Control of ASPP2/(53BP2L) protein levels by proteasomal degradation modulates p53 apoptotic function.EGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy.Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212.Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1.Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation.Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis.Royal jelly protects from taxol-induced testicular damages via improvement of antioxidant status and up-regulation of E2f1.Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death.TP53INP1 inhibits hypoxia-induced vasculogenic mimicry formation via the ROS/snail signalling axis in breast cancer.The Role of JMY in p53 Regulation.
P2860
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P2860
Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@ast
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@en
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@nl
type
label
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@ast
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@en
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@nl
prefLabel
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@ast
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@en
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@nl
P2093
P356
P1476
Novel link between E2F and p53 ...... iptionally upregulated by E2F.
@en
P2093
P2888
P304
P356
10.1038/SJ.CDD.4401575
P577
2005-04-01T00:00:00Z
P5875
P6179
1023902650