Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. - Wikidata - wikimedia - TriplyDB

Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals.

Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals.

http://www.wikidata.org/entity/Q34394494

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Strategies for developing novel therapeutics for sensorineural hearing loss.Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells Quo vadis, hair cell regeneration?Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.Stem Cell Therapy for Sensorineural Hearing Loss, Still Alive?Beyond generalized hair cells: molecular cues for hair cell types The genetics of hair cell development and regeneration Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Inner ear symptoms and disease: pathophysiological understanding and therapeutic options The cochlear implant: historical aspects and future prospects Sensory hair cell development and regeneration: similarities and differences Inducing brain regeneration from within: in vivo reprogramming of endogenous somatic cells into neurons MiR-210 promotes sensory hair cell formation in the organ of corti.Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells Hair cell regeneration after ATOH1 gene therapy in the cochlea of profoundly deaf adult guinea pigs.Micro-optical coherence tomography of the mammalian cochlea Co-administration of cisplatin and furosemide causes rapid and massive loss of cochlear hair cells in mice.A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear p27Kip1 knockdown induces proliferation in the organ of Corti in culture after efficient shRNA lentiviral transduction Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.Transcription factor STOX1 regulates proliferation of inner ear epithelial cells via the AKT pathway Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor Return of function after hair cell regeneration Curing hearing loss: Patient expectations, health care practitioners, and basic science.In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction.Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea.Adenovector-mediated hair cell regeneration is affected by promoter type.Optimizing atoh1-induced vestibular hair cell regeneration.Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation Hair cell stereociliary bundle regeneration by espin gene transduction after aminoglycoside damage and hair cell induction by Notch inhibition Nonviral Reprogramming of Human Wharton's Jelly Cells Reveals Differences Between ATOH1 Homologues.DAPT mediates atoh1 expression to induce hair cell-like cells.Functional evaluation of a cell replacement therapy in the inner ear.Manipulating cell fate in the cochlea: a feasible therapy for hearing loss.

P2860

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P2860

Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals.

http://www.wikidata.org/entity/Q34394494

description

2005 nî lūn-bûn

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2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2005 թվականի փետրվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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type

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Auditory hair cell replacement ...... gene therapy in deaf mammals.

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Nature Medicine

P1476

Auditory hair cell replacement ...... gene therapy in deaf mammals.

@en

P2093

David F Dolan

http://www.w3.org/2001/XMLSchema#string

Donald L Swiderski

http://www.w3.org/2001/XMLSchema#string

Douglas E Brough

http://www.w3.org/2001/XMLSchema#string

Karen A Abrashkin

http://www.w3.org/2001/XMLSchema#string

Kohei Kawamoto

http://www.w3.org/2001/XMLSchema#string

Masahiko Izumikawa

http://www.w3.org/2001/XMLSchema#string

Ryosei Minoda

http://www.w3.org/2001/XMLSchema#string

Yehoash Raphael

http://www.w3.org/2001/XMLSchema#string

P2860

Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B

Math1: an essential gene for the generation of inner ear hair cells

Math1 regulates development of the sensory epithelium in the mammalian cochlea

Making sense of making hair cells.

Migration of hyaline cells into the chick basilar papilla during severe noise damage.

The development of the vertebrate inner ear.

Cell fate specification in the inner ear.

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears.

Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1.

The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation.

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271-276

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10.1038/NM1193

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3

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11

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2005-02-13T00:00:00Z

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8020773

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15711559

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