A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis
about
Regulation of Bim in Health and DiseaseC/EBPβ regulates sensitivity to bortezomib in prostate cancer cells by inducing REDD1 and autophagosome-lysosome fusionMTI-101 treatment inducing activation of Stim1 and TRPC1 expression is a determinant of response in multiple myeloma.Combination of bortezomib and daunorubicin in the induction of apoptosis in T-cell acute lymphoblastic leukemiaDrugs acting on homeostasis: challenging cancer cell adaptation.Atg3 Overexpression Enhances Bortezomib-Induced Cell Death in SKM-1 CellCytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancersDual mTOR inhibitor MLN0128 suppresses Merkel cell carcinoma (MCC) xenograft tumor growth.Treatment of acquired drug resistance in multiple myeloma by combination therapy with XPO1 and topoisomerase II inhibitorsHistone deacetylase inhibitor panobinostat induces calcineurin degradation in multiple myeloma.XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma.Romidepsin for the treatment of non-Hodgkin's lymphoma.Rational combination strategies to enhance venetoclax activity and overcome resistance in hematologic malignancies.Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.RANK-RANKL interactions are involved in cell adhesion-mediated drug resistance in multiple myeloma cell lines.The role of VDR and BIM in potentiation of cytarabine-induced cell death in human AML blasts.Targeting executioner procaspase-3 with the procaspase-activating compound B-PAC-1 induces apoptosis in multiple myeloma cells.The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.(Immuno)proteasomes as therapeutic target in acute leukemia.Vorinostat and metformin sensitize EGFR-TKI resistant NSCLC cells via BIM-dependent apoptosis induction.
P2860
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P2860
A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@ast
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@en
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@nl
type
label
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@ast
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@en
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@nl
prefLabel
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@ast
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@en
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@nl
P2093
P2860
P1433
P1476
A Bim-targeting strategy overc ...... etween autophagy and apoptosis
@en
P2093
Liang Zhou
Maciej Kmieciak
Richard Jones
Shuang Chen
Steven Grant
Xin-Yan Pei
P2860
P304
P356
10.1182/BLOOD-2014-03-564534
P407
P577
2014-09-10T00:00:00Z