Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.
about
AMPK: An emerging target for modification of injury-induced pain plasticity.mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesiaTranslational control of nociception via 4E-binding protein 1Activation of mammalian target of rapamycin contributes to pain nociception induced in rats by BmK I, a sodium channel-specific modulatorAdenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.In vivo gene knockdown in rat dorsal root ganglia mediated by self-complementary adeno-associated virus serotype 5 following intrathecal delivery.Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat.mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.mTOR kinase: a possible pharmacological target in the management of chronic pain.Spatial and cellular characterization of mTORC1 activation after spinal cord injury reveals biphasic increase mainly attributed to microglia/macrophages.Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain.Autophagy impairment in a mouse model of neuropathic painMechanisms and pharmacology of neuropathic pain in multiple sclerosis.Intrathecal rapamycin attenuates morphine-induced analgesic tolerance and hyperalgesia in rats with neuropathic pain.mTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injuryNeuropathic pain in animal models of nervous system autoimmune diseases.Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat.Intact subepidermal nerve fibers mediate mechanical hypersensitivity via the activation of protein kinase C gamma in spared nerve injury.Activation of mammalian target of rapamycin mediates rat pain-related responses induced by BmK I, a sodium channel-specific modulator.Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury.PI3 Kinase regulation of neural regeneration and muscle hypertrophy after spinal cord injury.Drug repositioning: playing dirty to kill pain.Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain.Targeting AMPK for the Alleviation of Pathological Pain.mTOR and Erk1/2 Signaling in the Cerebrospinal Fluid-Contacting Nucleus is Involved in Neuropathic Pain.Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitizationTranslational Control Mechanisms in Persistent Pain.Peripheral Synthesis of an Atypical Protein Kinase C Mediates the Enhancement of Excitability and the Development of Mechanical Hyperalgesia Produced by Nerve Growth Factor.The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat.Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury.
P2860
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P2860
Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@ast
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@en
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@nl
type
label
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@ast
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@en
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@nl
prefLabel
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@ast
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@en
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@nl
P2093
P2860
P1433
P1476
Mammalian target of rapamycin ...... ed with neuropathy in the rat.
@en
P2093
Anthony H Dickenson
Curtis O Asante
Victoria C Wallace
P2860
P304
P356
10.1016/J.JPAIN.2010.03.013
P577
2010-05-08T00:00:00Z