Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences
about
The human IgE repertoireHuman IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteinsMultiple independent IgE epitopes on the highly allergenic grass pollen allergen Phl p 5.A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties.Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodiesDevelopment trends for generation of single-chain antibody fragments.Isolation of Mal d 1 and Api g 1 - specific recombinant antibodies from mouse IgG Fab fragment libraries - Mal d 1-specific antibody exhibits cross-reactivity against Bet v 1.High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum.Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments.Hybridization-based antibody cDNA recovery for the production of recombinant antibodies identified by repertoire sequencing.Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering.Phage display peptide libraries: deviations from randomness and correctives.Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding.
P2860
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P2860
Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences
description
2012 nî lūn-bûn
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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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Transferring the characteristi ...... es by trapping CDRH3 sequences
@ast
Transferring the characteristi ...... es by trapping CDRH3 sequences
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Transferring the characteristi ...... es by trapping CDRH3 sequences
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type
label
Transferring the characteristi ...... es by trapping CDRH3 sequences
@ast
Transferring the characteristi ...... es by trapping CDRH3 sequences
@en
Transferring the characteristi ...... es by trapping CDRH3 sequences
@nl
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Transferring the characteristi ...... es by trapping CDRH3 sequences
@ast
Transferring the characteristi ...... es by trapping CDRH3 sequences
@en
Transferring the characteristi ...... es by trapping CDRH3 sequences
@nl
P2093
P2860
P1433
P1476
Transferring the characteristi ...... es by trapping CDRH3 sequences
@en
P2093
Franck Gueneau
Marie Kosco-Vilbois
Nicolas Fischer
Sophie Venet
Sébastien Calloud
Vanessa Buatois
P2860
P304
P356
10.1371/JOURNAL.PONE.0043471
P407
P577
2012-08-24T00:00:00Z