Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain - Wikidata - wikimedia - TriplyDB

Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain

Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain

http://www.wikidata.org/entity/Q34400848

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Contemporary murine models in preclinical astrocytoma drug development A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma.Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit.Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production.Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells Therapeutic efficacy of aldoxorubicin in an intracranial xenograft mouse model of human glioblastoma.Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme.Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells.A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.Differential regulation of metabolism by nitric oxide and S-nitrosothiols in endothelial cells.Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas 5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits.Expression and clinical significance of cytochrome c oxidase subunit IV in colorectal cancer patients.Mitochondrial oncobioenergetic index: A potential biomarker to predict progression from indolent to aggressive prostate cancer.Integration of cellular bioenergetics with mitochondrial quality control and autophagy.The overexpression of hypomethylated miR-663 induces chemotherapy resistance in human breast cancer cells by targeting heparin sulfate proteoglycan 2 (HSPG2).Temozolomide promotes genomic and phenotypic changes in glioblastoma cells.Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition.Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide.Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma.miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma.Metabolic reprogramming of the tumor.Current evidence of temozolomide and bevacizumab in treatment of gliomas.Temozolomide-based combination for advanced neuroendocrine neoplasms: a systematic review of the literature.Prediction of Response to Temozolomide in Low-Grade Glioma Patients Based on Tumor Size Dynamics and Genetic Characteristics.Clinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects.Identification of Small Molecule Inhibitors of Human Cytochrome c Oxidase That Target Chemoresistant Glioma Cells.Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress.Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide.Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase.Downregulation of cytochrome c oxidase 1 induced radioresistance in esophageal squamous cell carcinoma

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P2860

Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain

http://www.wikidata.org/entity/Q34400848

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2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年论文

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Acquisition of temozolomide ch ...... drial electron transport chain

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Journal of Biological Chemistry

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Acquisition of temozolomide ch ...... drial electron transport chain

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Aimee Landar

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Anne Diers

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Claudia R Oliva

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G Yancey Gillespie

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P2860

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Genomic and proteomic profiling of responses to toxic metals in human lung cells.

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer

Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

CD133 is a marker of bioenergetic stress in human glioma

Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1.

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