Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo - Wikidata - wikimedia - TriplyDB

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

http://www.wikidata.org/entity/Q34401362

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BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability.Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.

P2860

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Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

http://www.wikidata.org/entity/Q34401362

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@ast

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@en

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@nl

type

label

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@ast

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@en

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@nl

prefLabel

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@ast

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@en

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@nl

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Nucleic Acids Research

P1476

Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo

@en

P2093

Adam J L Cook

http://www.w3.org/2001/XMLSchema#string

Christine W Y Yee

http://www.w3.org/2001/XMLSchema#string

Christopher J Jolly

http://www.w3.org/2001/XMLSchema#string

George Sharbeen

http://www.w3.org/2001/XMLSchema#string

Joanna Raftery

http://www.w3.org/2001/XMLSchema#string

K K Edwin Lau

http://www.w3.org/2001/XMLSchema#string

P2860

Maturation stage and proliferation-dependent expression of dUTPase in human T cells

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits

dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae.

The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species

DNA mismatch repair

Identification of a consensus cyclin-dependent kinase phosphorylation site unique to the nuclear form of human deoxyuridine triphosphate nucleotidohydrolase

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

P304

8120-8130

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scholarly article

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10.1093/NAR/GKQ682

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22

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38

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2010-08-12T00:00:00Z

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45640124

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20705648

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3001060

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