Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.
about
Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channelsStructure-based discovery of opioid analgesics with reduced side effects.High throughput screening technologies for ion channelsGlobal analysis reveals families of chemical motifs enriched for HERG inhibitorsAllosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.Automated design of ligands to polypharmacological profiles.Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.Fluorogenic probe for the human Ether-a-Go-Go-Related Gene potassium channel imagingThe cardiac safety of aripiprazole treatment in patients at high risk for torsade: a systematic review with a meta-analytic approach.Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis.A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain.Novel intramolecular photoinduced electron transfer-based probe for the Human Ether-a-go-go-Related Gene (hERG) potassium channel.Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, AntillatoxinAstemizole Derivatives as Fluorescent Probes for hERG Potassium Channel ImagingNovel cell-free high-throughput screening method for pharmacological tools targeting K+ channels.Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain.Approaches for probing allosteric interactions at 7 transmembrane spanning receptors.Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures.Cardiotoxicity screening: a review of rapid-throughput in vitro approaches.Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin.Evidence for the hERG Liability of Antihistamines, Antipsychotics, and Anti-Infective Agents: A Systematic Literature Review From the ARITMO Project.Single channel and ensemble hERG conductance measured in droplet bilayers.Effects of the benzodiazepine GABAA α1-preferring antagonist 3-isopropoxy-β-carboline hydrochloride (3-ISOPBC) on alcohol seeking and self-administration in baboons.Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.hERG Blockade by Iboga Alkaloids.
P2860
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P2860
Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of human Ether- ...... ademic drug-discovery setting.
@ast
Identification of human Ether- ...... ademic drug-discovery setting.
@en
Identification of human Ether- ...... ademic drug-discovery setting.
@nl
type
label
Identification of human Ether- ...... ademic drug-discovery setting.
@ast
Identification of human Ether- ...... ademic drug-discovery setting.
@en
Identification of human Ether- ...... ademic drug-discovery setting.
@nl
prefLabel
Identification of human Ether- ...... ademic drug-discovery setting.
@ast
Identification of human Ether- ...... ademic drug-discovery setting.
@en
Identification of human Ether- ...... ademic drug-discovery setting.
@nl
P2093
P2860
P356
P1476
Identification of human Ether- ...... cademic drug-discovery setting
@en
P2093
Bryan L Roth
Sandy Hufeisen
Thomas Mangano
Vincent Setola
P2860
P304
P356
10.1089/ADT.2010.0331
P577
2010-12-01T00:00:00Z