Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
about
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolismCharacterization of testis-specific isoenzyme of human pyruvate dehydrogenaseThe remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexesPhosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphologyTargeting Cancer Metabolism - Revisiting the Warburg EffectsTargeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?Structures of the human pyruvate dehydrogenase complex cores: a highly conserved catalytic center with flexible N-terminal domains.Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases.3D electron microscopy reveals the variable deposition and protein dynamics of the peripheral pyruvate dehydrogenase component about the core.Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferaseOrganization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 componentsDown-regulation of pyruvate dehydrogenase phosphatase in obese subjects is a defect that signals insulin resistanceInactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen speciesInvestigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormoneRole of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvationThe complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombeDysregulated pyruvate dehydrogenase complex in Zucker diabetic fatty rats.PGC-1α and fasting-induced PDH regulation in mouse skeletal muscleThermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR GammaThe pyruvate dehydrogenase complexes: structure-based function and regulation.Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapiesCloning and functions analysis of a pyruvate dehydrogenase kinase in Brassica napus.Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth.Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation.Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets.Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase.Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases.Elucidation of the interaction loci of the human pyruvate dehydrogenase complex E2·E3BP core with pyruvate dehydrogenase kinase 1 and kinase 2 by H/D exchange mass spectrometry and nuclear magnetic resonanceExpression of pyruvate dehydrogenase is an independent prognostic marker in gastric cancerCarbohydrate metabolism is perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK) activation, and peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) suppression.Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency.Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis.The emerging role of proteolysis in mitochondrial quality control and the etiology of Parkinson's disease.Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise.Pyruvate Dehydrogenase Kinases in the Nervous System: Their Principal Functions in Neuronal-glial Metabolic Interaction and Neuro-metabolic Disorders.Intrinsic protein kinase activity in mitochondrial oxidative phosphorylation complexes.Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases.Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexiaDecreased expression of pyruvate dehydrogenase A1 predicts an unfavorable prognosis in ovarian carcinoma.
P2860
Q24300524-32115924-A291-4BDB-843E-E9D25C001D10Q24302051-12F35C04-EE0A-43E4-868D-A52DDE0E3D98Q24555057-B7195C64-4FD1-402D-A923-9CFA26A5DCD4Q24675079-845CC59D-4B49-4336-98B9-19540F944763Q26738876-61CFA65A-E330-49F1-8B0C-FF629A0F05A4Q26774957-D2C47FD5-A83F-41D2-AF83-839B1C0B6C7CQ27303634-B8D37A9F-EEA0-4B80-B251-CAC9E5DC7300Q27930852-F1216575-6D43-4B6D-AD80-4ADC3E8BF228Q27935277-BFE58323-A456-4ABE-AE34-8CFCFA1867DAQ28180567-3D0E5B0A-2786-403D-A667-D7E7100A0F73Q28187388-AA0604DA-53DF-476A-80BD-E27DD34792C0Q28251109-6D0AD7D9-49EB-4AD3-BDE9-FE31BA4670B4Q28273438-BB05833C-9546-4458-BB56-9AFD0340D761Q28566344-B0ACEE69-8F27-4334-8B90-1C434D0F9A2EQ28588431-7E47FDDB-FCEE-4A3F-B280-393C103CD114Q33296914-C5883CDD-A42D-49E7-B987-A2E8B394C265Q33303658-8FE0964F-A00B-4580-A4AC-AE01DC83B3BAQ33567491-E2D6119B-EDFD-4E65-ADF9-B0A8B1D4C911Q33748280-077A74D5-1335-431F-AA0C-B393533EDB48Q33761130-31DE6BE4-0544-4E59-ABD6-EE93F02362EDQ33849207-59CA14DC-8075-4B8A-B79B-F7E47E7A6FFCQ33861599-09CA3949-0979-4E04-B708-423022336EB8Q33985291-B8FC1072-059D-4CEE-AEC9-4E31D851FA65Q34100946-FE5C052C-72C9-4941-8AA2-1EDD3F0D2CB4Q34249210-76C26625-4F90-4D7E-94B2-2129D73D57B1Q34393425-3A86D5B7-76AB-42AF-869A-54DED37DB326Q34557385-BC043FDA-92F5-4342-BBB0-FB47C56ED9CAQ34572847-B96F3620-4719-4A8D-882C-75525538B40BQ34972253-B8920FA0-AF5B-4546-8B99-26B31E0F944FQ35567679-67ABE683-21D7-452E-84EA-03B865C0287DQ35604967-14F2FCA2-0A50-4050-BD12-8078DE162E22Q35683716-D5C3B0DA-D104-46EE-8DAA-82A8DB0FBBEDQ35713627-AB111605-874B-49CA-B611-20443B508435Q35986574-93EF8EB4-2D9F-43AE-922A-6B78043DAE18Q36057621-A76C91DB-DA84-46AF-B3A1-7C473C87DD5BQ36460635-7911D2FA-E772-4F45-8E0B-7A00C84E054FQ36472557-071686B9-1532-4A7E-8466-5D836C8F89DCQ36743618-0BD94FAE-3E03-4A38-B140-202FB99C9ABEQ37016738-598CF853-7B94-41FC-B072-6C4EF65BEBB0Q37298324-98BDF5AF-3D5B-4187-AEA8-FD0C3FED6273
P2860
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@ast
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@en
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@nl
type
label
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@ast
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@en
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@nl
prefLabel
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@ast
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@en
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@nl
P2093
P1476
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms.
@en
P2093
Hiromasa Y
P356
10.1016/S0079-6603(01)70013-X
P577
2001-01-01T00:00:00Z