Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo.
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Gelatinase B/MMP-9 in Tumour Pathogenesis and ProgressionSelective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal CancerScribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary glandRaf kinases in cancer-roles and therapeutic opportunitiesNetwork analysis of breast cancer progression and reversal using a tree-evolving network algorithmCaveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathwayWhy don't we get more cancer? A proposed role of the microenvironment in restraining cancer progressionNetwork Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting.Coherent angular motion in the establishment of multicellular architecture of glandular tissues.DEAD-box helicase DP103 defines metastatic potential of human breast cancers.RORα suppresses breast tumor invasion by inducing SEMA3F expressionThe need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancerIncreased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathwaysIntegrin α3β1 as a breast cancer targetSerpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.Dynamic reciprocity between cells and their microenvironment in reproduction.Human breast cancer histoid: an in vitro 3-dimensional co-culture model that mimics breast cancer tissueInterconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response.Reversible Aptamer-Au Plasmon Rulers for Secreted Single Molecules.Metastasis prevention by targeting the dormant niche.The tumor microenvironment is a dominant force in multidrug resistance.Microengineered tumor models: insights & opportunities from a physical sciences-oncology perspectiveCRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasisNuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesisLaminin-111 Peptides Conjugated to Fibrin Hydrogels Promote Formation of Lumen Containing Parotid Gland Cell ClustersThe perivascular niche regulates breast tumour dormancy.NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals.Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2.Of plasticity and specificity: dialectics of the micro- and macro-environment and the organ phenotype.Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells.Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.Proteomic profiling of the tumor microenvironment: recent insights and the search for biomarkers.The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomasEngineering the extracellular matrix for clinical applications: endoderm, mesoderm, and ectoderm.A novel MCF-10A line allowing conditional oncogene expression in 3D culture.Expression, Regulation, and Effects of Interleukin-17f in the Human Ocular Surface.Metastasis: an early event in cancer progression.Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells.WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells.Pathways Involved in Formation of Mammary Organoid Architecture Have Keys to Understanding Drug Resistance and to Discovery of Druggable Targets.
P2860
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P2860
Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@ast
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@en
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@nl
type
label
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@ast
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@en
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@nl
prefLabel
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@ast
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@en
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@nl
P2093
P2860
P356
P1433
P1476
Raf-induced MMP9 disrupts tiss ...... sary for tumor growth in vivo.
@en
P2093
Alain Beliveau
Antonius A Koller
Emily I Chen
John Muschler
Joni D Mott
Mina J Bissell
Paul Yaswen
P2860
P304
P356
10.1101/GAD.1990410
P577
2010-12-01T00:00:00Z