DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target
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IGF-1 Receptor and Adhesion Signaling: An Important Axis in Determining Cancer Cell Phenotype and Therapy ResistanceEpigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.Oncogenic transformation of diverse gastrointestinal tissues in primary organoid cultureDecreased expression of 17β-hydroxysteroid dehydrogenase type 1 is associated with DNA hypermethylation in colorectal cancer located in the proximal colon.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisOncovirus Kaposi sarcoma herpesvirus (KSHV) represses tumor suppressor PDLIM2 to persistently activate nuclear factor κB (NF-κB) and STAT3 transcription factors for tumorigenesis and tumor maintenance.NF-κB and cancer: a paradigm of Yin-Yang.Differential roles of STAT3 in the initiation and growth of lung cancerThe tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesisNF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease.Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling.A microRNA 221- and 222-mediated feedback loop maintains constitutive activation of NFκB and STAT3 in colorectal cancer cells.Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling.PDLIM2 regulates transcription factor activity in epithelial-to-mesenchymal transition via the COP9 signalosome.Prioritization of SNPs for genome-wide association studies using an interaction model of genetic variation, gene expression, and trait variationInactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.PDLIM2 suppression efficiently reduces tumor growth and invasiveness of human castration-resistant prostate cancer-like cells.Essential function for PDLIM2 in cell polarization in three-dimensional cultures by feedback regulation of the β1-integrin-RhoA signaling axis.Molecular determinants of PDLIM2 in suppressing HTLV-I Tax-mediated tumorigenesis.Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling.Exome and transcriptome sequencing identifies loss of PDLIM2 in metastatic colorectal cancers.PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D.Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation.
P2860
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P2860
DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
DNA methylation-dependent repr ...... a potential therapeutic target
@ast
DNA methylation-dependent repr ...... a potential therapeutic target
@en
DNA methylation-dependent repr ...... a potential therapeutic target
@nl
type
label
DNA methylation-dependent repr ...... a potential therapeutic target
@ast
DNA methylation-dependent repr ...... a potential therapeutic target
@en
DNA methylation-dependent repr ...... a potential therapeutic target
@nl
prefLabel
DNA methylation-dependent repr ...... a potential therapeutic target
@ast
DNA methylation-dependent repr ...... a potential therapeutic target
@en
DNA methylation-dependent repr ...... a potential therapeutic target
@nl
P2093
P2860
P1433
P1476
DNA methylation-dependent repr ...... a potential therapeutic target
@en
P2093
Gutian Xiao
Jing Jiang
Michael J Grusby
Thomas E Smithgall
Zhaoxia Qu
P2860
P304
P356
10.1158/0008-5472.CAN-09-3263
P407
P577
2010-02-09T00:00:00Z