Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
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Update in Cystic Fibrosis 2014Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung diseaseAnimal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and DivergencesThe Role of Serine Proteases and Antiproteases in the Cystic Fibrosis LungQuantification of heterogeneity in lung disease with image-based pulmonary function testing.Nanoparticle uptake by airway phagocytes after fungal spore challenge in murine allergic asthma and chronic bronchitisAirway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.Anti-inflammatory effects of secondary metabolites of marine Pseudomonas sp. in human neutrophils are through inhibiting P38 MAPK, JNK, and calcium pathways.Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction.A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease.Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice.Emphysema Is Common in Lungs of Cystic Fibrosis Lung Transplantation Patients: A Histopathological and Computed Tomography Study.Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.Putting lung function and physiology into perspective: cystic fibrosis in adults.Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections.Animal models of polymicrobial pneumonia.Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.SPX-101 is a Novel ENaC-targeted Therapeutic for Cystic Fibrosis that Restores Mucus Transport.Recent developments of genetically encoded optical sensors for cell biology.Prevalence and Responsiveness to Treatment of Lung Abnormalities on Chest Computed Tomography in Patients With Microscopic Polyangiitis: A Multicenter, Longitudinal, Retrospective Study of One Hundred Fifty Consecutive Hospital-Based Japanese PatienAirway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases.Immunomodulatory Cell Therapy to Target Cystic Fibrosis Inflammation.Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis.Genetic Deletion and Pharmacological Inhibition of PI3K γ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease.(-)-Epigallocatechin-3-gallate Reduces Cigarette Smoke-Induced Airway Neutrophilic Inflammation and Mucin Hypersecretion in Rats.Neutrophil activation and enhanced release of granule products in HIV-TB immune reconstitution inflammatory syndrome.From fibrosis to diagnosis: a paediatric case of microscopic polyangiitis and review of the literature.Profile of the ProAxsis active neutrophil elastase immunoassay for precision medicine in chronic respiratory disease.Infection is Not Required for Mucoinflammatory Lung Disease in CFTR-knockout Ferrets.Lung disease phenotypes caused by overexpression of combinations of α-, β-, and γ-subunits of the epithelial sodium channel in mouse airways.Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.A FRET-based biosensor for the detection of neutrophil elastase.A new player in the game: epithelial cathepsin S in early cystic fibrosis lung disease.Neutrophil extracellular traps promote lipopolysaccharide-induced airway inflammation and mucus hypersecretion in mice.Airway Epithelium Dysfunction in Cystic Fibrosis and COPD.
P2860
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P2860
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@ast
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@en
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@nl
type
label
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@ast
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@en
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@nl
prefLabel
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@ast
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@en
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@nl
P2093
P2860
P50
P1476
Lack of neutrophil elastase re ...... ic fibrosis-like lung disease.
@en
P2093
Abderrazzaq Belaaouaj
Alexander H Dalpke
Claudius J Wagner
Jolanthe Schatterny
Marcus A Mall
Michael Weitnauer
Stefanie Gehrig
Stephanie Hirtz
P2860
P304
P356
10.1164/RCCM.201311-1932OC
P407
P577
2014-05-01T00:00:00Z