Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
about
Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegansIsolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesisCharacterization of solanesyl and decaprenyl diphosphate synthases in mice and humansA nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevityCLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegansEvolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in miceRegulation of physiological rates in Caenorhabditis elegans by a tRNA-modifying enzyme in the mitochondriaA regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegansA mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegansProtective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis.Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis.Sip2p and its partner snf1p kinase affect aging in S. cerevisiae.Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!Plastoquinone and Ubiquinone in Plants: Biosynthesis, Physiological Function and Metabolic EngineeringMechanisms of aging-related proteinopathies in Caenorhabditis elegansThe cell biology of agingReversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- miceThe genetics of caloric restriction in Caenorhabditis elegansThe genetics of aging-- implications for pharmacogenomics.Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.Differential gene expression in breast cancer cell lines and stroma-tumor differences in microdissected breast cancer biopsies revealed by display array analysis.Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.Genetic and pharmacological factors that influence reproductive aging in nematodesTRPM channels are required for rhythmicity in the ultradian defecation rhythm of C. elegansA Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegansEvidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans.Revolution in mitochondrial medicine.Aging: Dial M for Mitochondriaclk-1, mitochondria, and physiological rates.Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis.A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice.CLK-1/Coq7p is a DMQ mono-oxygenase and a new member of the di-iron carboxylate protein family.Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphataseMitochondria, aging and longevity--a new perspective.The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteinsMeasurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans.Quinones in long-lived clk-1 mutants of Caenorhabditis elegans.A reduction in age-enhanced gluconeogenesis extends lifespan.
P2860
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P2860
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@ast
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@en
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@nl
type
label
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@ast
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@en
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@nl
prefLabel
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@ast
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@en
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@nl
P2093
P1433
P1476
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
@en
P2093
P304
P356
10.1126/SCIENCE.275.5302.980
P407
P577
1997-02-01T00:00:00Z