Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
about
Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study.Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolismalphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor proteinInvolvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell deathSenile plaque neurites in Alzheimer disease accumulate amyloid precursor proteinHumanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130The amyloid precursor protein: beyond amyloidGinkgolide B inhibits the neurotoxicity of prions or amyloid-beta1-42Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionPreclinical Alzheimer disease: identification of cases at risk among cognitively intact older individualsAlzheimer's disease pathologic cascades: who comes first, what drives whatInconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseThe multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foesA γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APPAPP processing in Alzheimer's diseaseThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseNeuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicityTau protein kinase I is essential for amyloid beta-protein-induced neurotoxicityAmyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's diseaseThe neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosisOverexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's diseaseAn integrated approach of differential mass spectrometry and gene ontology analysis identified novel proteins regulating neuronal differentiation and survivalGalantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptorsThe amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy.Estradiol prevents olfactory dysfunction induced by A-β 25-35 injection in hippocampus.Increased gene expression of Alzheimer disease beta-amyloid precursor protein in senescent cultured fibroblasts.Abeta42 mutants with different aggregation profiles induce distinct pathologies in DrosophilaCan oral infection be a risk factor for Alzheimer's disease?Identification of small molecule inhibitors of beta-amyloid cytotoxicity through a cell-based high-throughput screening platform.The Sixth International Conference on Alzheimer's disease, Amsterdam, The Netherlands, July 1998. The amyloid cascade hypothesis debate: emerging consensus on the role of A beta and amyloid in Alzheimer's disease.Genetic risk factors in Alzheimer's diseaseEnzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brainLysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.Mitochondrial superoxide: a key player in Alzheimer's diseaseAlzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: requirement for tau and APP.Alzheimer's disease and the amyloid beta protein: What is the role of amyloid?Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury.Transgenic Drosophila models of Alzheimer's disease and tauopathies
P2860
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P2860
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
description
1989 nî lūn-bûn
@nan
1989 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@ast
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@en
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@nl
type
label
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@ast
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@en
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@nl
prefLabel
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@ast
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@en
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@nl
P2093
P356
P1433
P1476
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.
@en
P2093
Oster-Granite ML
Villa-Komaroff L
Yankner BA
P304
P356
10.1126/SCIENCE.2474201
P407
P577
1989-07-01T00:00:00Z