Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
about
T cell-intrinsic function of the noncanonical NF-κB pathway in the regulation of GM-CSF expression and experimental autoimmune encephalomyelitis pathogenesis.Highly diverse TCRα chain repertoire of pre-immune CD8⁺ T cells reveals new insights in gene recombination.HMGB1 in health and disease.Epigenetic regulation of monoallelic rearrangement (allelic exclusion) of antigen receptor genes.Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element.The multiple shark Ig H chain genes rearrange and hypermutate autonomously.T-cell receptor α enhancer is inactivated in αβ T lymphocytes.Complete cis Exclusion upon Duplication of the Eμ Enhancer at the Immunoglobulin Heavy Chain Locus.DNA double-strand breaks relieve USF-mediated repression of Dβ2 germline transcription in developing thymocytes.Regulation of TCRβ allelic exclusion by gene segment proximity and accessibilityInfluence of a CTCF-Dependent Insulator on Multiple Aspects of Enhancer-Mediated Chromatin OrganizationA discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoiresAn ectopic CTCF-dependent transcriptional insulator influences the choice of Vβ gene segments for VDJ recombination at TCRβ locus.Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cellsEpigenetics and the adaptive immune responseTRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cellsVκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region.Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J RecombinationNoncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences.H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinaseEpigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'.Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia.Modeling of the RAG reaction mechanism.Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination.Clinical, immunologic, and genetic characteristics of RAG mutations in 15 Chinese patients with SCID and Omenn syndrome.Tcrd Rearrangement Redirects a Processive Tcra Recombination Program to Expand the Tcra Repertoire.Control of V(D)J Recombination through Transcriptional Elongation and Changes in Locus Chromatin Structure and Nuclear Organization.Chromatin Domain Organization of the TCRb Locus and Its Perturbation by Ectopic CTCF Binding.An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments.Activation of Mouse Tcrb: Uncoupling RUNX1 Function from Its Cooperative Binding with ETS1.Epigenetic modifications of the VH region after DJH recombination in Pro-B cells.High-sequence diversity and structural conservation in the human T-cell receptor β junctional region during thymic development.
P2860
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P2860
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@ast
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@en
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@nl
type
label
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@ast
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@en
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@nl
prefLabel
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@ast
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@en
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@nl
P2093
P2860
P356
P1476
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
@en
P2093
Alicia J Little
Bingtao Hao
David G Schatz
Eugene M Oltz
Joydeep K Banerjee
Michael S Krangel
Yanhong Ji
P2860
P304
P356
10.1084/JEM.20101136
P407
P577
2010-11-29T00:00:00Z