Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity
about
From Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormonesGuanylin and functional coupling proteins in the hepatobiliary system of rat and guinea pigCompartmentalization of extracellular cGMP determines absorptive or secretory responses in the rat jejunum.A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic ConstipationThe uroguanylin system and human disease.Prosequence switching: an effective strategy to produce biologically active E. coli heat-stable enterotoxin STh.A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis.Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.Uroguanylin, an intestinal natriuretic peptide, is delivered to the kidney as an unprocessed propeptide.The role of the rectum in osmoregulation and the potential effect of renoguanylin on SLC26a6 transport activity in the Gulf toadfish (Opsanus beta).The pharmacokinetics, pharmacodynamics, clinical efficacy, safety and tolerability of linaclotide.Constella™(EU)-Linzess™(USA): the last milestone in the long journey of the peptide linaclotide and its implications for the future of peptide drugs.Current understanding of guanylin peptides actions.Emerging treatments in Neurogastroenterology: Perspectives of guanylyl cyclase C agonists use in functional gastrointestinal disorders and inflammatory bowel diseases.Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer.Uroguanylin regulates net fluid secretion via the NHE2 isoform of the Na/H+ exchanger in an intestinal cellular model.A novel role for uroguanylin in the regulation of sodium balance.Increased urinary excretion of uroguanylin in patients with congestive heart failure.Role of the prosequence of guanylin.Therapeutically targeting guanylate cyclase-C: computational modeling of plecanatide, a uroguanylin analog.Clarification of linaclotide pharmacology presented in a recent clinical study of plecanatide.Taking a lesson from microbial diarrheagenesis in the management of chronic constipation.Plecanatide, an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract, is safe and well-tolerated in single doses.Guanylin peptides regulate electrolyte and fluid transport in the Gulf toadfish (Opsanus beta) posterior intestine.Duodenal bicarbonate secretion in rats: stimulation by intra-arterial and luminal guanylin and uroguanylin.Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation.Effect of uroguanylin on potassium and bicarbonate transport in rat renal tubules.Plecanatide: a new guanylate cyclase agonist for the treatment of chronic idiopathic constipation.Clinical utility of plecanatide in the treatment of chronic idiopathic constipationThe Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia
P2860
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P2860
Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Regulation of intestinal urogu ...... d responses by mucosal acidity
@ast
Regulation of intestinal urogu ...... d responses by mucosal acidity
@en
Regulation of intestinal urogu ...... d responses by mucosal acidity
@nl
type
label
Regulation of intestinal urogu ...... d responses by mucosal acidity
@ast
Regulation of intestinal urogu ...... d responses by mucosal acidity
@en
Regulation of intestinal urogu ...... d responses by mucosal acidity
@nl
prefLabel
Regulation of intestinal urogu ...... d responses by mucosal acidity
@ast
Regulation of intestinal urogu ...... d responses by mucosal acidity
@en
Regulation of intestinal urogu ...... d responses by mucosal acidity
@nl
P2093
P2860
P356
P1476
Regulation of intestinal urogu ...... d responses by mucosal acidity
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.6.2705
P407
P577
1997-03-01T00:00:00Z