Novel molecular mechanism involving alpha1D (Cav1.3) L-type calcium channel in autoimmune-associated sinus bradycardia.
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Long QT Syndrome: An Emerging Role for Inflammation and ImmunityPerinatal and postnatal expression of Cav1.3 α1D Ca²⁺ channel in the rat heartSilencing of Cav1.2 gene in neonatal cardiomyocytes by lentiviral delivered shRNAG protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel.Role of calcium channels in congenital heart blockProtein kinase C activation inhibits Cav1.3 calcium channel at NH2-terminal serine 81 phosphorylation site.Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts.Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathwaysFunctional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupusIron overload decreases CaV1.3-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation.Congenital heart block: evidence for a pathogenic role of maternal autoantibodiesAtrioventricular conduction delay in fetuses exposed to anti-SSA/Ro and anti-SSB/La antibodies: a magnetocardiography studyLeft Atrial Inexcitability in Children With Congenital Lupus-Induced Complete Atrioventricular Block.Impaired Ca2+ homeostasis is associated with atrial fibrillation in the alpha1D L-type Ca2+ channel KO mouse.Genesis and regulation of the heart automaticity.Calreticulin negatively regulates the surface expression of Cav1.3 L-type calcium channel.Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channelCardiac electrophysiology in mice: a matter of size.T-type channels in the sino-atrial and atrioventricular pacemaker mechanism.Arrhythmias in the developing heart.Autoimmune channelopathies as a novel mechanism in cardiac arrhythmias.Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea-pigs.CaV1.3 L-type Ca2+ channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na+ current.Expression of skeletal muscle Na(V)1.4 Na channel isoform in canine cardiac Purkinje myocytes.Phosphorylation of the consensus sites of protein kinase A on alpha1D L-type calcium channel.Application of Whole Exome Sequencing in the Clinical Diagnosis and Management of Inherited Cardiovascular Diseases in Adults.L-type Cav1.3 channels regulate ryanodine receptor-dependent Ca2+ release during sino-atrial node pacemaker activity.Identification of discrete epitopes of Ro52p200 and association with fetal cardiac conduction system manifestations in a rodent model.Towards computational modelling of the human foetal electrocardiogram: normal sinus rhythm and congenital heart block.
P2860
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P2860
Novel molecular mechanism involving alpha1D (Cav1.3) L-type calcium channel in autoimmune-associated sinus bradycardia.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Novel molecular mechanism invo ...... -associated sinus bradycardia.
@ast
Novel molecular mechanism invo ...... -associated sinus bradycardia.
@en
Novel molecular mechanism involving alpha1D
@nl
type
label
Novel molecular mechanism invo ...... -associated sinus bradycardia.
@ast
Novel molecular mechanism invo ...... -associated sinus bradycardia.
@en
Novel molecular mechanism involving alpha1D
@nl
prefLabel
Novel molecular mechanism invo ...... -associated sinus bradycardia.
@ast
Novel molecular mechanism invo ...... -associated sinus bradycardia.
@en
Novel molecular mechanism involving alpha1D
@nl
P2093
P1433
P1476
Novel molecular mechanism invo ...... e-associated sinus bradycardia
@en
P2093
Ghayath Baroudi
Yongxia Qu
Yuankun Yue
P304
P356
10.1161/CIRCULATIONAHA.104.517326
P407
P577
2005-06-06T00:00:00Z