Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
about
Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.Toward a better understanding of ADHD: LPHN3 gene variants and the susceptibility to develop ADHDDescription and validation of a dynamical systems model of presynaptic serotonin function: genetic variation, brain activation and impulsivityCandidate genes and neuropsychological phenotypes in children with ADHD: review of association studiesThe 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouseAdvances in molecular genetic studies of attention deficit hyperactivity disorder in ChinaSerotonin Transporter and Tryptophan Hydroxylase Gene Variations Mediate Working Memory Deficits of Cocaine UsersThe effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: a retrospective analysis.Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.A genetic study of ADHD and activity level in infancy.Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traitsGenetic influences on attention deficit hyperactivity disorder symptoms from age 2 to 3: a quantitative and molecular genetic investigation.Molecular genetics of attention deficit hyperactivity disorder.Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder.Pharmacogenetics of antidepressant response.Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls.Influence of candidate genes on attention problems in children: a longitudinal studyThe analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes.Tryptophan hydroxylase(2) gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans.Tryptophan research in panic disorderGenome-wide analysis of attention deficit hyperactivity disorder in Norway.Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder.Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention.Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57/Bl6 mice.Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2.Advances in tryptophan hydroxylase-2 gene expression regulation: new insights into serotonin-stress interaction and clinical implicationsRole of the serotonin system in ADHD: treatment implications.Somnambulism induced by quetiapine: two case reports and a review of the literature.Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population.Molecular genetics of attention-deficit/hyperactivity disorder: an overviewGenetic determinants of aggression and impulsivity in humans.Genetic and epigenetic dysregulation of imprinted genes in the brain.Genetic and neurocognitive foundations of emotion abnormalities in bipolar disorder.Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder.A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression.5'-Untranslated region of the tryptophan hydroxylase-2 gene harbors an asymmetric bidirectional promoter but not internal ribosome entry site in vitro.Regulation of tryptophan hydroxylase-2 gene expression by a bipartite RE-1 silencer of transcription/neuron restrictive silencing factor (REST/NRSF) binding motif.Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2.Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro.Two cases of somnambulism induced by quetiapine.
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P2860
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
@ast
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
@en
type
label
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
@ast
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
@en
prefLabel
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
@ast
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
@en
P2093
P2860
P356
P1433
P1476
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.MP.4001698
P407
P577
2005-10-01T00:00:00Z