ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity.
about
Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact miceIdentification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists.Minireview: Estrogen receptor-beta: mechanistic insights from recent studies.Synthesis of fluorinated δ-lactams via cycloisomerization of gem-difluoropropargyl amidesEstrogen receptor beta selective nonsteroidal estrogens: seeking clinical indications.In silico prediction of estrogen receptor subtype binding affinity and selectivity using statistical methods and molecular docking with 2-arylnaphthalenes and 2-arylquinolines.Versatility or promiscuity: the estrogen receptors, control of ligand selectivity and an update on subtype selective ligands.The unexpected science of estrogen receptor-beta selective agonists: a new class of anti-inflammatory agents?Estrogen receptor β ligands: recent advances and biomedical applications.Multiple-targeting and conformational selection in the estrogen receptor: computation and experiment.The role of estrogen signaling in a mouse model of inflammatory bowel disease: a Helicobacter hepaticus model.Structural and Functional Diversity of Estrogen Receptor Ligands.Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells.The novel resveratrol analogue HS-1793 induces apoptosis via the mitochondrial pathway in murine breast cancer cellsMutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7.Binding of small-molecule ligands to proteins: "what you see" is not always "what you get".Selective estrogen receptor modulators for BPH: new factors on the ground.Snap deconvolution: An informatics approach to high-throughput discovery of catalytic reactions.Synthesis of phenol and quinone metabolites of benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer.Benzothiepin-derived molecular scaffolds for estrogen receptor modulators: synthesis and antagonistic effects in breast cancer cells.Syntheses of dibenzo[d,d']benzo[2,1-b:3,4-b']difuran derivatives and their application to organic field-effect transistors.Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate.Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion.Quantitative structure-activity relationships for a series of selective estrogen receptor-beta modulators.Synthesis of 2-phenylnaphthalenes from styryl-2-methoxybenzenes.The development of a short route to the API ropinirole hydrochloride.Discovery of a series of 2-phenylnaphthalenes as firefly luciferase inhibitors
P2860
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P2860
ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@ast
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@en
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@nl
type
label
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@ast
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@en
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@nl
prefLabel
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@ast
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@en
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@nl
P2093
P356
P1476
ERbeta ligands. 3. Exploiting ...... to achieve ERbeta selectivity.
@en
P2093
Cuijian Yang
Eric S Manas
Heather A Harris
James C Keith
Richard E Mewshaw
Richard J Edsall
Ruth A Henderson
Zhang B Xu
P304
P356
10.1021/JM058173S
P407
P577
2005-06-01T00:00:00Z