Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development. - Wikidata - wikimedia - TriplyDB

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

http://www.wikidata.org/entity/Q34425414

about

RGS18 is a myeloerythroid lineage-specific regulator of G-protein-signalling molecule highly expressed in megakaryocytes The molecular mechanisms that control thrombopoiesis Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes Thrombopoietin signal transduction requires functional JAK2, not TYK2 Comparative analyses of megakaryocytes derived from cord blood and bone marrow.Thrombopoietin as a drug: biologic expectations, clinical realities, and future directions.Effects of sepsis on neonatal thrombopoiesis.An ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominance Pathobiology of secondary immune thrombocytopenia.Pharmacokinetic and pharmacodynamic modeling of pegylated thrombopoietin mimetic peptide (PEG-TPOm) after single intravenous dose administration in healthy subjects.Platelets prevent acute hepatitis induced by anti-fas antibody.Developmental differences in megakaryocytopoiesis are associated with up-regulated TPO signaling through mTOR and elevated GATA-1 levels in neonatal megakaryocytes.Thrombopoietin receptor levels in tumor cell lines and primary tumors Romiplostim dose response in patients with immune thrombocytopenia.Low or undetectable TPO receptor expression in malignant tissue and cell lines derived from breast, lung, and ovarian tumors.Thrombopoietin from beginning to end.Protein kinase C δ deficiency enhances megakaryopoiesis and recovery from thrombocytopenia.The Eltrombopag antitumor effect on hepatocellular carcinoma.Thrombocytopenia in chronic liver disease.The role of bone marrow microenvironment in platelet production and their implications for the treatment of thrombocytopenic diseases.Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation.Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes.Thrombopoietin and platelet development Purification, cDNA cloning, and characterization of a new serpin with megakaryocyte maturation activity.Cell fate determination from stem cells.Deficiency in thrombopoietin induction after liver surgery is associated with postoperative liver dysfunction.The genetics of common variation affecting platelet development, function and pharmaceutical targeting.Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation.H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets Cytokine signaling in the differentiation of innate effector cells Lineage commitment in the progeny of murine hematopoietic preprogenitor cells: influence of thrombopoietin and interleukin 5.Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity.In vitro megakaryocyte production and platelet biogenesis: state of the art Myelodysplastic syndrome hematopoietic stem cell.A novel role for thrombopoietin in regulating osteoclast development in humans and mice.Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells.Megakaryothrombopoiesis during ex vivo expansion of human cord blood CD34+ cells using thrombopoietin.

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P2860

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

http://www.wikidata.org/entity/Q34425414

description

1995 nî lūn-bûn

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1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1995 թվականի ապրիլին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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type

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

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P2093

C Lofton-Day

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D Zucker-Franklin

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J McCarty

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K Kaushansky

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M J Jorgensen

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N Fox

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N Lin

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V C Broudy

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P2860

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

Multifactor stimulation of megakaryocytopoiesis: effects of interleukin 6.

Action of interleukin-3, G-CSF, and GM-CSF on highly enriched human hematopoietic progenitor cells: synergistic interaction of GM-CSF plus G-CSF.

Correlation of in vitro and in vivo biological activities during the partial purification of thrombopoietin.

Thrombocytopenia in c-mpl-deficient mice.

Creation of phosphorylation sites in proteins: construction of a phosphorylatable human interferon alpha.

Conditions controlling the proliferation of haemopoietic stem cells in vitro.

Human interleukin 6 is a direct promoter of maturation of megakaryocytes in vitro.

Growth of human hemopoietic colonies in response to recombinant gibbon interleukin 3: comparison with human recombinant granulocyte and granulocyte-macrophage colony-stimulating factor

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3234-3238

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10.1073/PNAS.92.8.3234

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8

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