CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.
about
Understanding a substrate's product regioselectivity in a family of enzymes: a case study of acetaminophen binding in cytochrome P450sStructural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects.Inhibition of baicalin on metabolism of phenacetin, a probe of CYP1A2, in human liver microsomes and in rats.Hydroxylation and N-dechloroethylation of Ifosfamide and deuterated Ifosfamide by the human cytochrome p450s and their commonly occurring polymorphisms.Development of an in vitro system with human liver microsomes for phenotyping of CYP2C9 genetic polymorphisms with a mechanism-based inactivatorEnzyme source effects on CYP2C9 kinetics and inhibitionNanoscale electron transport measurements of immobilized cytochrome P450 proteins.Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismPreparation, characterization, and substrate metabolism of gold-immobilized cytochrome P450 2C9Cooperative properties of cytochromes P450.Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone.Functional analysis of phenylalanine residues in the active site of cytochrome P450 2C9.
P2860
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P2860
CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@ast
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@en
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@nl
type
label
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@ast
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@en
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@nl
prefLabel
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@ast
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@en
CYP2C9 genotype-dependent effe ...... ation in the CYP2C9.3 variant.
@nl
P2093
P356
P1476
CYP2C9 genotype-dependent effe ...... vation in the CYP2C9.3 variant
@en
P2093
Allan E Rettie
Carrie M Mosher
Charles W Locuson
Dan A Rock
Matthew A Hummel
Timothy S Tracy
P304
P356
10.1124/MOL.105.013763
P577
2005-06-13T00:00:00Z