Exploiting protein-protein interaction networks for genome-wide disease-gene prioritization
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Review on Graph Clustering and Subgraph Similarity Based Analysis of Neurological DisordersA transcriptome-proteome integrated network identifies endoplasmic reticulum thiol oxidoreductase (ERp57) as a hub that mediates bone metastasisA DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactomeMolecular interaction networks in the analyses of sequence variation and proteomics data.MUFFINN: cancer gene discovery via network analysis of somatic mutation data.Hope for GWAS: relevant risk genes uncovered from GWAS statistical noise.Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.GUILDify: a web server for phenotypic characterization of genes through biological data integration and network-based prioritization algorithms.Analysis of the robustness of network-based disease-gene prioritization methods reveals redundancy in the human interactome and functional diversity of disease-genes.Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studiesGraph-theoretical model of global human interactome reveals enhanced long-range communicability in cancer networks.Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells.Computational analysis of multimorbidity between asthma, eczema and rhinitis.FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies.Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing.Pathway analyses and understanding disease associations.A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.Protein-protein interaction networks (PPI) and complex diseases.A large-scale benchmark of gene prioritization methodsComparing human-Salmonella with plant-Salmonella protein-protein interaction predictionsEnriching Traditional Protein-protein Interaction Networks with Alternative Conformations of Proteins.Network propagation: a universal amplifier of genetic associations.Network-Guided Key Gene Discovery for a Given Cellular Process.Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information.Genetic and functional characterization of disease associations explains comorbidity.Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer NetworksThrombin stimulates insulin secretion via protease-activated receptor-3Substantial contribution of genetic variation in the expression of transcription factors to phenotypic variation revealed by eRD-GWAS.DDA: A Novel Network-Based Scoring Method to Identify Disease-Disease Associations.Phenotype-driven gene prioritization for rare diseases using graph convolution on heterogeneous networks.EviNet: a web platform for network enrichment analysis with flexible definition of gene sets.Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology
P2860
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P2860
Exploiting protein-protein interaction networks for genome-wide disease-gene prioritization
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Exploiting protein-protein int ...... de disease-gene prioritization
@ast
Exploiting protein-protein int ...... de disease-gene prioritization
@en
Exploiting protein-protein int ...... de disease-gene prioritization
@nl
type
label
Exploiting protein-protein int ...... de disease-gene prioritization
@ast
Exploiting protein-protein int ...... de disease-gene prioritization
@en
Exploiting protein-protein int ...... de disease-gene prioritization
@nl
prefLabel
Exploiting protein-protein int ...... de disease-gene prioritization
@ast
Exploiting protein-protein int ...... de disease-gene prioritization
@en
Exploiting protein-protein int ...... de disease-gene prioritization
@nl
P2860
P1433
P1476
Exploiting protein-protein int ...... de disease-gene prioritization
@en
P2093
Baldo Oliva
Emre Guney
P2860
P304
P356
10.1371/JOURNAL.PONE.0043557
P407
P577
2012-09-21T00:00:00Z