Checkpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation.
about
The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase.Mitotic UV irradiation induces a DNA replication-licensing defect that potentiates G1 arrest response.Mismatch repair proteins recruited to ultraviolet light-damaged sites lead to degradation of licensing factor Cdt1 in the G1 phase.Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation.
P2860
Checkpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation.
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@ast
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@en
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@nl
type
label
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@ast
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@en
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@nl
prefLabel
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@ast
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@en
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation.
@nl
P2093
P2860
P1433
P1476
Checkpoint kinase ATR phosphor ...... Cdt1 following UV irradiation
@en
P2093
Hiroki Sakaguchi
Masayuki Morino
Takashi Ishii
Takeshi Maeda
Toshihiro Takami
Yasushi Shiomi
Yoshinori Yasutani
P2860
P304
P356
10.1371/JOURNAL.PONE.0046480
P407
P577
2012-09-28T00:00:00Z