Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks
about
The metagenomic telescopeRad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaksA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseNot All DDRs Are Created Equal: Non-Canonical DNA Damage ResponsesDouble strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamilyHistone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repairPathogenesis of ataxia-telangiectasia: the next generation of ATM functionsABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complexStructure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signalingThe DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisEnvisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairDouble-strand break repair and colorectal cancer: gene variants within 3' UTRs and microRNAs binding as modulators of cancer risk and clinical outcomeRare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening studyDestabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung diseaseMechanisms for Structural Variation in the Human GenomeImplementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source.Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.Hereditary breast cancer: ever more pieces to the polygenic puzzle.The role of the human psoralen 4 (hPso4) protein complex in replication stress and homologous recombination.E1B and E4 oncoproteins of adenovirus antagonize the effect of apoptosis inducing factorRAD50 targeting impairs DNA damage response and sensitizes human breast cancer cells to cisplatin therapyLinking chromosome duplication and segregation via sister chromatid cohesionEndoplasmic reticulum stress pathway PERK-eIF2α confers radioresistance in oropharyngeal carcinoma by activating NF-κB.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeXPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.Autoinhibition of bacteriophage T4 Mre11 by its C-terminal domain.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.NBS1 plays a synergistic role with telomerase in the maintenance of telomeres in Arabidopsis thaliana.An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forksSpatiotemporal dynamics of early DNA damage response proteins on complex DNA lesions.Regulation of DNA damage responses and cell cycle progression by hMOB2.Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy.Role of lamin b1 in chromatin instabilityBcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiationReplication fork integrity and intra-S phase checkpoint suppress gene amplification.Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation.ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.
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P2860
Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@ast
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@en
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@nl
type
label
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@ast
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@en
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@nl
prefLabel
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@ast
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@en
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@nl
P2860
P1433
P1476
Mre11-Rad50-Nbs1 conformations ...... es at DNA double-strand breaks
@en
P2093
Gareth J Williams
Susan P Lees-Miller
P2860
P304
P356
10.1016/J.DNAREP.2010.10.001
P577
2010-10-28T00:00:00Z