about
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complexAn intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acidThe Wnt-dependent signaling pathways as target in oncology drug discoveryRole of beta-catenin in synaptic vesicle localization and presynaptic assemblyAtomic model of human Rcd-1 reveals anarmadillo-like-repeat protein with in vitro nucleic acid binding propertiesPygopus residues required for its binding to Legless are critical for transcription and developmentThe tuberin-hamartin complex negatively regulates beta-catenin signaling activityScribble interacts with beta-catenin to localize synaptic vesicles to synapsesThe function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model.Dynamic aspects of CNS synapse formation.Inhibition of β-catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-catenin/TCF-1 complex: critical role of STAT-3.The tuberous sclerosis complex genes in tumor development.Gene expression profiling in the discovery, optimization and development of novel drugs: one universal screening platform.Wnt signaling and human diseases: what are the therapeutic implications?Links between signal transduction, transcription and adhesion in epithelial bud development.The T-box transcription factor Midline regulates wing development by repressing wingless and hedgehog in DrosophilaAssessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination.Novel TCF-binding sites specify transcriptional repression by Wnt signallingBone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancerCompetitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger.CBP/p300 are bimodal regulators of Wnt signaling.Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle.Cellular conditioning and activation of beta-catenin signaling by the FPB prostanoid receptor.C-terminal-binding protein directly activates and represses Wnt transcriptional targets in DrosophilaWnt/β-Catenin Mediates AICAR Effect to Increase GATA3 Expression and Inhibit Adipogenesis.The chromatin remodelers ISWI and ACF1 directly repress Wingless transcriptional targets.Structures of designed armadillo repeat proteins binding to peptides fused to globular domains.Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy.Exon 3 mutations of CTNNB1 drive tumorigenesis: a review.Chemopreventive effect of dietary curcumin on inflammation-induced colorectal carcinogenesis in mice.Loureirin B inhibits the proliferation of hepatic stellate cells and the Wnt/β-catenin signaling pathway by regulating miR-148-3p
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
beta-catenin: molecular plasticity and drug design.
@ast
beta-catenin: molecular plasticity and drug design.
@en
beta-catenin: molecular plasticity and drug design.
@nl
type
label
beta-catenin: molecular plasticity and drug design.
@ast
beta-catenin: molecular plasticity and drug design.
@en
beta-catenin: molecular plasticity and drug design.
@nl
prefLabel
beta-catenin: molecular plasticity and drug design.
@ast
beta-catenin: molecular plasticity and drug design.
@en
beta-catenin: molecular plasticity and drug design.
@nl
P1476
beta-catenin: molecular plasticity and drug design
@en
P2093
D L Daniels
K Eklof Spink
P304
P356
10.1016/S0968-0004(01)01952-1
P577
2001-11-01T00:00:00Z