The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.

Item
http://www.wikidata.org/entity/Q34435367
Dovitinib: rationale, preclinical and early clinical data in urothelial carcinoma of the bladder.Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNAEpithelial mesenchymal transition status is associated with anti-cancer responses towards receptor tyrosine-kinase inhibition by dovitinib in human bladder cancer cells.Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis.High Throughput Screening Identifies a Novel Compound Protecting Cardiomyocytes from Doxorubicin-Induced DamageStructure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogsMechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform.A Receptor Tyrosine Kinase Inhibitor, Dovitinib (TKI-258), Enhances BMP-2-Induced Osteoblast Differentiation In Vitro.A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.Assessment of Immunomodulatory Activities and in vitro Toxicity of New Quinolone 7-ethyl 9-ethyl-6-oxo-6,9-dihydro[1,2,5]selenadiazolo[3,4-h]quinoline-7-carboxylate.Structural bioinformatics-based identification of EGFR inhibitor gefitinib as a putative lead compound for BACE.Dovitinib (CHIR258, TKI258): structure, development and preclinical and clinical activity.Dovitinib enhances temozolomide efficacy in glioblastoma cells.Dovitinib induces mitotic defects and activates the G2 DNA damage checkpoint.Genotoxic effects of the antimalarial drug lumefantrine in human lymphocytes in vitro and computational prediction of the mechanism associated with its interaction with DNA.An update on current management of advanced renal cell cancer, biomarkers, and future directions
P2860

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.

Item
http://www.wikidata.org/entity/Q34435367
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@ast
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@en
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@nl
type
label
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@ast
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@en
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@nl
prefLabel
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@ast
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@en
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
The anticancer multi-kinase in ...... merase I and topoisomerase II.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932