The ubiquitin-proteasome pathway and its role in cancer.
about
SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinomaNovel RING E3 ubiquitin ligases in breast cancerUbiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1Akt is negatively regulated by the MULAN E3 ligaseAutoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migrationUbiquitin is a novel substrate for human insulin-degrading enzymeBRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localizationLoss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expressionCancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancyColorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome PathwayAberrant nuclear factor-kappa B activity in acute myeloid leukemia: from molecular pathogenesis to therapeutic targetRegulation of ERBB3/HER3 signaling in cancerNovel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade gliomaA quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness.Pulsed high-intensity focused ultrasound enhances apoptosis and growth inhibition of squamous cell carcinoma xenografts with proteasome inhibitor bortezomib.A design principle underlying the paradoxical roles of E3 ubiquitin ligasesDifferential expression proteomics of human colon cancer.Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes.Phase II study of bortezomib in patients with previously treated advanced urothelial tract transitional cell carcinoma: CALGB 90207.Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatinDiscovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cellsIn vivo accumulation of Helicobacter pylori products, NOD1, ubiquitinated proteins and proteasome in a novel cytoplasmic structureProtein post-translational modifications: In silico prediction tools and molecular modeling.Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse modelTranscription alterations of members of the ubiquitin-proteasome network in prostate carcinoma.Protacs for treatment of cancer.An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundancePartial proteasome inhibitors induce hair follicle growth by stabilizing β-cateninProtein degradation machinery is present broadly during early development in the sea urchin.Lysine 419 targets human glucocorticoid receptor for proteasomal degradation.The ubiquitin peptidase UCHL1 induces G0/G1 cell cycle arrest and apoptosis through stabilizing p53 and is frequently silenced in breast cancer.Ubiquitination-dependent regulation of signaling receptors in cancer.Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways.The triterpenoid pristimerin induces U87 glioma cell apoptosis through reactive oxygen species-mediated mitochondrial dysfunctionHDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivoUBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylationA phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas
P2860
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P2860
The ubiquitin-proteasome pathway and its role in cancer.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The ubiquitin-proteasome pathway and its role in cancer.
@ast
The ubiquitin-proteasome pathway and its role in cancer.
@en
The ubiquitin-proteasome pathway and its role in cancer.
@nl
type
label
The ubiquitin-proteasome pathway and its role in cancer.
@ast
The ubiquitin-proteasome pathway and its role in cancer.
@en
The ubiquitin-proteasome pathway and its role in cancer.
@nl
prefLabel
The ubiquitin-proteasome pathway and its role in cancer.
@ast
The ubiquitin-proteasome pathway and its role in cancer.
@en
The ubiquitin-proteasome pathway and its role in cancer.
@nl
P356
P1476
The ubiquitin-proteasome pathway and its role in cancer.
@en
P2093
Aparna Mani
Edward P Gelmann
P304
P356
10.1200/JCO.2005.05.081
P407
P577
2005-07-01T00:00:00Z