Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
about
"Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAsThe Rise of CRISPR/Cas for Genome Editing in Stem CellsNuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingRendering the Intractable More Tractable: Tools from Caenorhabditis elegans Ripe for Import into Parasitic NematodesTargeting Non-Coding RNAs in Plants with the CRISPR-Cas Technology is a Challenge yet Worth AcceptingResources for the design of CRISPR gene editing experimentsHow specific is CRISPR/Cas9 really?Minimizing off-Target Mutagenesis Risks Caused by Programmable NucleasesA new age in functional genomics using CRISPR/Cas9 in arrayed library screeningEnabling functional genomics with genome engineeringThe New State of the Art: Cas9 for Gene Activation and RepressionDesigned nucleases for targeted genome editingAdvances in CRISPR-Cas9 genome engineering: lessons learned from RNA interferenceOff-target Effects in CRISPR/Cas9-mediated Genome EngineeringQuantifying on- and off-target genome editingGenetic screens and functional genomics using CRISPR/Cas9 technologySynthetic RNAs for Gene Regulation: Design Principles and Computational ToolsDiscovery of a proteinaceous cellular receptor for a norovirusPatterns of CRISPR/Cas9 activity in plants, animals and microbesEngineering Sugar Utilization and Microbial Tolerance toward Lignocellulose ConversionCRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent InfectionsGenomic Characterization of Metformin Hepatic ResponseGenome engineering in the yeast pathogen Candida glabrata using the CRISPR-Cas9 systemBCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesisStructure Principles of CRISPR-Cas Surveillance and Effector ComplexesEditing of the urease gene by CRISPR-Cas in the diatom Thalassiosira pseudonanaIntegrated genetic and pharmacologic interrogation of rare cancersCHOPCHOP v2: a web tool for the next generation of CRISPR genome engineeringEasi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Generating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing.CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalisCRISPR/Cas9: Transcending the Reality of Genome Editing.Reliable CRISPR/Cas9 Genome Engineering in Caenorhabditis elegans Using a Single Efficient sgRNA and an Easily Recognizable Phenotype.Generation of heritable germline mutations in the jewel wasp Nasonia vitripennis using CRISPR/Cas9The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia.pKAMA-ITACHI Vectors for Highly Efficient CRISPR/Cas9-Mediated Gene Knockout in Arabidopsis thaliana.CRISPR/Cas9: From Genome Engineering to Cancer Drug DiscoveryFlexible CRISPR library construction using parallel oligonucleotide retrieval.
P2860
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P2860
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@ast
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@en
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@nl
type
label
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@ast
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@en
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@nl
prefLabel
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@ast
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@en
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
@nl
P2093
P2860
P356
P1433
P1476
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation
@en
P2093
Benjamin L Ebert
Daniel B Graham
David E Root
Ella Hartenian
John G Doench
Ramnik J Xavier
Zuzana Tothova
P2860
P2888
P304
P356
10.1038/NBT.3026
P577
2014-09-03T00:00:00Z