A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity. - Wikidata - wikimedia - TriplyDB

A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity.

A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity.

http://www.wikidata.org/entity/Q34437037

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Medial prefrontal cortex 5-HT(2A) density is correlated with amygdala reactivity, response habituation, and functional coupling Identifying serotonergic mechanisms underlying the corticolimbic response to threat in humans Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour Alternative splicing and extensive RNA editing of human TPH2 transcripts Genetic influences on the neural and physiological bases of acute threat: A research domain criteria (RDoC) perspective.Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing Tryptophan hydroxylase-2: an emerging therapeutic target for stress disorders The effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: a retrospective analysis.Imaging phenotypes of major depressive disorder: genetic correlates Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease A functional Tph2 C1473G polymorphism causes an anxiety phenotype via compensatory changes in the serotonergic system.Neuroimaging: technologies at the interface of genes, brain, and behavior.Associations between prefrontal γ-aminobutyric acid concentration and the tryptophan hydroxylase isoform 2 gene, a panic disorder risk allele in women.Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgen receptor gene predict amygdala reactivity in men Acute 5-HT reuptake blockade potentiates human amygdala reactivity.Feature-based representations of emotional facial expressions in the human amygdala.Pharmacogenetics of antidepressant response.TPH2 5'- and 3'-regulatory polymorphisms are differentially associated with HPA axis function and self-injurious behavior in rhesus monkeys.Functional gene polymorphisms in the serotonin system and traumatic life events modulate the neural basis of fear acquisition and extinction Combinations of single nucleotide polymorphisms in neuroendocrine effector and receptor genes predict chronic fatigue syndrome.Perceived social support moderates the link between threat-related amygdala reactivity and trait anxiety The amygdala: inside and out.An exploration of the serotonin system in antisocial boys with high levels of callous-unemotional traits.Tryptophan hydroxylase(2) gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans.Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders.Affective cognition and its disruption in mood disorders.Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.Gender moderates the association between 5-HTTLPR and decision-making under ambiguity but not under risk.Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder.Decreased fragile X mental retardation protein expression underlies amygdala dysfunction in carriers of the fragile X premutation.Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function Attachment-security priming attenuates amygdala activation to social and linguistic threat Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder.Imaging genetics of mood disorders.Top-Down Control of Serotonin Systems by the Prefrontal Cortex: A Path toward Restored Socioemotional Function in Depression TPH2 G/T polymorphism is associated with hyperphagia, IQ, and internalizing problems in Prader-Willi syndrome.Variation in the Williams syndrome GTF2I gene and anxiety proneness interactively affect prefrontal cortical response to aversive stimuli.A Novel Interaction between Tryptophan Hydroxylase 2 (TPH2) Gene Polymorphism (rs4570625) and BDNF Val66Met Predicts a High-Risk Emotional Phenotype in Healthy Subjects Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

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P2860

A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity.

http://www.wikidata.org/entity/Q34437037

description

2005 nî lūn-bûn

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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prefLabel

A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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Molecular Psychiatry

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A regulatory variant of the hu ...... ne biases amygdala reactivity.

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Brown SM

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Dahl RE

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Ferrell RE

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Hariri AR

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Manuck SB

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Peet E

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Williamson DE

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P2860

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

Synthesis of serotonin by a second tryptophan hydroxylase isoform

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

Serotonin transporter genetic variation and the response of the human amygdala

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression.

Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia.

Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression.

A susceptibility gene for affective disorders and the response of the human amygdala.

A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity.

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10.1038/SJ.MP.4001716

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