Nonamyloid aggregates arising from mature copper/zinc superoxide dismutases resemble those observed in amyotrophic lateral sclerosis
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Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosisOligomerization of Cu,Zn-Superoxide Dismutase (SOD1) by Docosahexaenoic Acid and Its Hydroperoxides In Vitro: Aggregation Dependence on Fatty Acid Unsaturation and Thiols.Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypesDecreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS.Cupric ions induce the oxidation and trigger the aggregation of human superoxide dismutase 1SOD1 aggregation in ALS mice shows simplistic test tube behavior.Fibrillation precursor of superoxide dismutase 1 revealed by gradual tuning of the protein-folding equilibrium.ALS-linked misfolded SOD1 species have divergent impacts on mitochondria.Early steps in thermal unfolding of superoxide dismutase 1 are similar to the conformational changes associated with the ALS-associated A4V mutation.Comparison of serum Concentration of Se, Pb, Mg, Cu, Zn, between MS patients and healthy controls.Protein misfolding in the late-onset neurodegenerative diseases: common themes and the unique case of amyotrophic lateral sclerosis.SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology: New and Renascent Themes.Polyanion binding accelerates the formation of stable and low-toxic aggregates of ALS-linked SOD1 mutant A4V.Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzymePrognostic role of "prion-like propagation" in SOD1-linked familial ALS: an alternative view.Many roads lead to Rome? Multiple modes of Cu,Zn superoxide dismutase destabilization, misfolding and aggregation in amyotrophic lateral sclerosis.Partially native intermediates mediate misfolding of SOD1 in single-molecule folding trajectories.Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells.Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS
P2860
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P2860
Nonamyloid aggregates arising from mature copper/zinc superoxide dismutases resemble those observed in amyotrophic lateral sclerosis
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@ast
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@en
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@nl
type
label
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@ast
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@en
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@nl
prefLabel
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@ast
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@en
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@nl
P2093
P2860
P356
P1476
Nonamyloid aggregates arising ...... amyotrophic lateral sclerosis
@en
P2093
Elizabeth M Meiering
Hamid R Badiei
Jessica A O Rumfeldt
Kristin Dimmick
Ming Sze Tong
Peter B Stathopulos
Vassili Karanassios
Young-Mi Hwang
P2860
P304
41701-41711
P356
10.1074/JBC.M110.113696
P407
P50
P577
2010-10-25T00:00:00Z