Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans.
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Role of reactive metabolites in the circulation in extrahepatic toxicityHuman hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expressionGenetic polymorphisms of human flavin-containing monooxygenase 3: implications for drug metabolism and clinical perspectivesDifferential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomesIsoform distinct time-, dose-, and castration-dependent alterations in flavin-containing monooxygenase expression in mouse liver after 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment.Characterization of human flavin-containing monooxygenase (FMO) 3 and FMO5 expressed as maltose-binding protein fusionsHuman flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism.The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumptionFlavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.Developmental and tissue-specific expression of human flavin-containing monooxygenases 1 and 3.Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny.Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjectsInter-individual variation in flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors.Genetic and Non-genetic Factors Associated with Protein Abundance of Flavin-containing Monooxygenase 3 in Human Liver.Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry Perspective.Drug metabolism by flavin-containing monooxygenases of human and mouse.Flavin-containing monooxygenase 3 polymorphisms in 13 ethnic populations from Europe, East Asia and sub-Saharan Africa: frequency and linkage analysis.Alternative promoters and repetitive DNA elements define the species-dependent tissue-specific expression of the FMO1 genes of human and mouse.Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.Effect of human flavin-containing monooxygenase 3 polymorphism on the metabolism of aurora kinase inhibitors.Effect of pregnancy on a measure of FMO3 activity.Characterization of moclobemide N-oxidation in human liver microsomes.S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes.Cytochrome P450 and Non-Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics.Metabolism and disposition of the dipeptidyl peptidase IV inhibitor teneligliptin in humans.Metabolism of nicotine in rat lung microvascular endothelial cells.Effect of Flavin-Containing Monooxygenase Genotype, Mouse Strain, and Gender on Trimethylamine N-oxide Production, Plasma Cholesterol Concentration, and an Index of Atherosclerosis.Flavin-containing monooxygenase 3 gene polymorphisms in Turkish population.Development of a physiologically based pharmacokinetic model to predict the effects of flavin-containing monooxygenase 3 (FMO3) polymorphisms on itopride exposure.Overexpression of flavin-containing monooxygenase 5 predicts poor prognosis in patients with colorectal cancer.Influence of FMO1 and 3 polymorphisms on serum olanzapine and its N-oxide metabolite in psychiatric patients.
P2860
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P2860
Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans.
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@ast
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@en
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@nl
type
label
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@ast
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@en
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@nl
prefLabel
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@ast
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@en
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@nl
P2093
P1476
Quantitation and kinetic prope ...... xygenases 3 and 5 from humans.
@en
P2093
P356
10.1016/S0009-2797(97)00055-0
P577
1997-08-01T00:00:00Z