Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.
about
Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspringReorganization of chromosome architecture in replicative cellular senescenceA novel single-cell method provides direct evidence of persistent DNA damage in senescent cells and aged mammalian tissues14-3-3 proteins restrain the Exo1 nuclease to prevent overresection.SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediatesReactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice.How Diet Intervention via Modulation of DNA Damage Response through MicroRNAs May Have an Effect on Cancer Prevention and Aging, an in Silico Study.Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex.Sharpening the ends for repair: mechanisms and regulation of DNA resection.A novel role for DNA single-strand breaks in senescence and neoplastic escape of epithelial cells.The unfolded protein response and cellular senescence. A review in the theme: cellular mechanisms of endoplasmic reticulum stress signaling in health and disease.Genetics of melanoma progression: the rise and fall of cell senescence.Lipid (per) oxidation in mitochondria: an emerging target in the ageing process?Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA.Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons.p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells.Radiation-induced unrepairable DSBs: their role in the late effects of radiation and possible applications to biodosimetry.Organ reserve, excess metabolic capacity, and aging.Short Leukocyte Telomere Length Predicts Albuminuria Progression in Individuals With Type 2 Diabetes.APE1 deficiency promotes cellular senescence and premature aging features.The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.Role of sphingolipids in senescence: implication in aging and age-related diseases
P2860
Q21146665-1F55B80A-7D46-4FAC-9BCB-CBB19059796FQ27335944-B26159AD-D593-46DE-8B9F-DA1902498641Q34550064-8E92CDC2-7C5F-4E2D-929E-E793E08FB4B7Q35583181-20CC2E4C-D764-411C-A4BB-D4D09B3A4592Q35842523-ABCCB0B9-7FE4-4A87-9CCE-02CF8D270C01Q36203750-BA9A914E-669B-427E-9EF0-1CC1CBA92C80Q36939317-5BF8FA9B-C373-4317-A4D8-2F21C3E97E6DQ36959122-46AEF6DB-E1AC-4D4D-9714-D104C7CCB41CQ37058602-28123749-C8A8-43A5-AD14-1268967871DFQ37346514-2D848440-5B8C-4EC8-A3F5-E91D18177649Q38300472-83472606-4DC0-418E-9061-635FA65B2142Q38589518-2034970A-301E-4D30-8B0A-B534CEC92199Q39328053-C4223F4F-ACD8-4D56-9191-244EEE545A1BQ39434311-88197BD3-CF99-4BB9-B207-0A2222EE3008Q41534319-25D9F039-6B6F-4DA0-B04C-F7FB914709CCQ41642304-AB297509-96F0-46B6-B46E-9154F19FD534Q48002597-CE15568E-D6BF-44E1-A638-B340388B8E44Q49557385-D6712ABE-731B-4999-B128-B2A782A05904Q50041770-9A00A22F-0C4D-4BA0-9A3C-C7219E4CACE8Q55318377-5BDBFAC8-E0AC-49C5-819D-2F8BE321F562Q55402216-254516B8-B6B3-42D8-B1D9-EC85DB566FFFQ55637473-BF347FED-AE17-421F-9AE6-593CA303154BQ57177438-D951990C-DB31-4CF6-A6D7-3D06F4DB0B42
P2860
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@ast
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@en
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@nl
type
label
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@ast
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@en
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@nl
prefLabel
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@ast
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@en
Irreparable telomeric DNA dama ...... ellular senescence and ageing.
@nl
P2093
P2860
P1476
Irreparable telomeric DNA dama ...... cellular senescence and ageing
@en
P2093
Francesca Rossiello
Marzia Fumagalli
Utz Herbig
P2860
P356
10.1016/J.GDE.2014.06.009
P577
2014-06-01T00:00:00Z