Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.
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Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblastsRegulation of cellular iron metabolismSystematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutationsHuman iron-sulfur cluster assembly, cellular iron homeostasis, and diseaseMolecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesisSplice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intoleranceIron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster deliveryThe role of mitochondria in cellular iron-sulfur protein biogenesis: mechanisms, connected processes, and diseasesErythroid heme biosynthesis and its disordersBMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelinSubstrate interactions with human ferrochelataseFunctional, structural, and spectroscopic characterization of a glutathione-ligated [2Fe-2S] cluster in poplar glutaredoxin C1The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activityIron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 of Trypanosoma brucei : Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite InfectivitySaccharomyces cerevisiae Grx6 and Grx7 are monothiol glutaredoxins associated with the early secretory pathway.New perspectives on the molecular basis of the interaction between oxygen homeostasis and iron metabolismRedox regulation of mitochondrial functionThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingRegulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2RNA silencing of mitochondrial m-Nfs1 reduces Fe-S enzyme activity both in mitochondria and cytosol of mammalian cellsIron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S clusterBOLA1 is an aerobic protein that prevents mitochondrial morphology changes induced by glutathione depletionA Glutaredoxin-BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly MachineryZebrafish in hematology: sushi or science?Iron and porphyrin trafficking in heme biogenesis.Novel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish modelsIron-regulatory proteins: molecular biology and pathophysiological implicationsPosttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery.Glutaredoxins: roles in iron homeostasisA disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's dRedox regulation of cell survival by the thioredoxin superfamily: an implication of redox gene therapy in the heart.A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis.Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulationThe physiological functions of iron regulatory proteins in iron homeostasis - an update.Studying disorders of vertebrate iron and heme metabolism using zebrafish.The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen.SLC25 Family Member Genetic Interactions Identify a Role for HEM25 in Yeast Electron Transport Chain Stability.Erythropoietin signaling regulates heme biosynthesis.Heme metabolism and erythropoiesis.Special delivery: distributing iron in the cytosol of mammalian cells.
P2860
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P2860
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@ast
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@en
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@nl
type
label
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@ast
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@en
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@nl
prefLabel
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@ast
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@en
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@nl
P2093
P2860
P356
P1433
P1476
Deficiency of glutaredoxin 5 r ...... for vertebrate haem synthesis.
@en
P2093
Alan J Davidson
Barry H Paw
Bettina Schmid
Bruce Barut
George C Shaw
Gerhard J Weber
Heidi Schubert
Helen Foott
James Palis
Jenna L Galloway
P2860
P2888
P304
P356
10.1038/NATURE03887
P407
P577
2005-08-01T00:00:00Z
P5875
P6179
1034332443