SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation.
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Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock systemDNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoterDEC1 modulates the circadian phase of clock gene expressionAbundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activationDisturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant miceStra13 homodimers repress transcription through class B E-box elementsBasic helix-loop-helix protein DEC1 promotes chondrocyte differentiation at the early and terminal stagesDec1 and Dec2 expression is disrupted in the suprachiasmatic nuclei of Clock mutant miceSHARP1/DEC2 inhibits adipogenic differentiation by regulating the activity of C/EBPmSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expressionHelt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous systemBasic helix-loop-helix transcription factor DEC1 negatively regulates cyclin D1.Anhedonic behavior in cryptochrome 2-deficient mice is paralleled by altered diurnal patterns of amygdala gene expression.Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway.A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation.Genomic organization and identification of promoter regions for the BDNF gene in the pond turtle Trachemys scripta elegans.The basic helix-loop-helix protein, sharp-1, represses transcription by a histone deacetylase-dependent and histone deacetylase-independent mechanism.The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter.Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP.Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex.Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.Cellular and molecular responses of cultured neurons to stressful stimuliThe transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancersbHLH-Orange Transcription Factors in Development and Cancer.Opposing actions of Per1 and Cry2 in the regulation of Per1 target gene expression in the liver and kidneyThe genomic response of the ipsilateral and contralateral cortex to stroke in aged rats.PI-3 kinase pathway can mediate the effect of TGF-beta1 in inducing the expression of SHARP-2 in LLC-PK1 cells.Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.The transcription factor DEC1 (BHLHE40/STRA13/SHARP-2) is negatively associated with TNM stage in non-small-cell lung cancer and inhibits the proliferation through cyclin D1 in A549 and BE1 cells.Regulation of basic helix-loop-helix transcription factors Dec1 and Dec2 by RORα and their roles in adipogenesis.Overexpression of fasciculation and elongation protein zeta-1 (FEZ1) induces a post-entry block to retroviruses in cultured cells.Sharp-1/DEC2 inhibits skeletal muscle differentiation through repression of myogenic transcription factors.Constitutive overexpression of the basic helix-loop-helix Nex1/MATH-2 transcription factor promotes neuronal differentiation of PC12 cells and neurite regeneration.Meta-analysis and profiling of cardiac expression modules.Networks of Cultured iPSC-Derived Neurons Reveal the Human Synaptic Activity-Regulated Adaptive Gene Program.Interaction between the skeletal muscle type 1 Na+ channel promoter E-box and an upstream repressor element. Release of repression by myogenin.IL-1β-mediated up-regulation of DEC1 in human gingiva cells via the Akt pathway.SHARP-2/Stra13/DEC1 as a potential repressor of phosphoenolpyruvate carboxykinase gene expression.Angiogenin expression in human kidneys and Wilms' tumours: relationship with hypoxia and angiogenic factors.
P2860
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P2860
SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation.
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@ast
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@en
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@nl
type
label
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@ast
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@en
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@nl
prefLabel
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@ast
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@en
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@nl
P2093
P356
P1476
SHARPs: mammalian enhancer-of- ...... upled to neuronal stimulation.
@en
P2093
P304
P356
10.1006/MCNE.1997.0640
P577
1997-01-01T00:00:00Z